Zinc fingers and a green thumb: Manipulating gene expression in plants

David Segal, Justin T. Stege, Carlos F. Barbas

Research output: Contribution to journalArticle

27 Scopus citations

Abstract

Artificial transcription factors can be rapidly constructed from predefined zinc-finger modules to regulate virtually any gene. Stable, heritable up- and downregulation of endogenous genes has been demonstrated in transgenic plants. These advances promise new approaches for creating functional knockouts and conditional overexpression, and for other gene discovery and manipulation applications in plants.

Original languageEnglish (US)
Pages (from-to)163-168
Number of pages6
JournalCurrent Opinion in Plant Biology
Volume6
Issue number2
DOIs
StatePublished - Apr 2003
Externally publishedYes

ASJC Scopus subject areas

  • Plant Science

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