Zinc fingers and a green thumb: Manipulating gene expression in plants

David Segal; Justin T. Stege; Carlos F. Barbas

doi:10.1016/S1369-5266(03)00007-4

Zinc fingers and a green thumb: Manipulating gene expression in plants

David Segal, Justin T. Stege, Carlos F. Barbas

Research output: Contribution to journal › Article › peer-review

29 Scopus citations

Abstract

Artificial transcription factors can be rapidly constructed from predefined zinc-finger modules to regulate virtually any gene. Stable, heritable up- and downregulation of endogenous genes has been demonstrated in transgenic plants. These advances promise new approaches for creating functional knockouts and conditional overexpression, and for other gene discovery and manipulation applications in plants.

Original language	English (US)
Pages (from-to)	163-168
Number of pages	6
Journal	Current Opinion in Plant Biology
Volume	6
Issue number	2
DOIs	https://doi.org/10.1016/S1369-5266(03)00007-4
State	Published - Apr 2003
Externally published	Yes

ASJC Scopus subject areas

Plant Science

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abstract = "Artificial transcription factors can be rapidly constructed from predefined zinc-finger modules to regulate virtually any gene. Stable, heritable up- and downregulation of endogenous genes has been demonstrated in transgenic plants. These advances promise new approaches for creating functional knockouts and conditional overexpression, and for other gene discovery and manipulation applications in plants.",

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Zinc fingers and a green thumb: Manipulating gene expression in plants

Abstract

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