Zinc fingers and a green thumb

Manipulating gene expression in plants

David Segal, Justin T. Stege, Carlos F. Barbas

Research output: Contribution to journalArticle

27 Citations (Scopus)

Abstract

Artificial transcription factors can be rapidly constructed from predefined zinc-finger modules to regulate virtually any gene. Stable, heritable up- and downregulation of endogenous genes has been demonstrated in transgenic plants. These advances promise new approaches for creating functional knockouts and conditional overexpression, and for other gene discovery and manipulation applications in plants.

Original languageEnglish (US)
Pages (from-to)163-168
Number of pages6
JournalCurrent Opinion in Plant Biology
Volume6
Issue number2
DOIs
StatePublished - Apr 2003
Externally publishedYes

Fingerprint

zinc finger motif
gene expression
genes
transgenic plants
transcription factors

ASJC Scopus subject areas

  • Plant Science

Cite this

Zinc fingers and a green thumb : Manipulating gene expression in plants. / Segal, David; Stege, Justin T.; Barbas, Carlos F.

In: Current Opinion in Plant Biology, Vol. 6, No. 2, 04.2003, p. 163-168.

Research output: Contribution to journalArticle

Segal, David ; Stege, Justin T. ; Barbas, Carlos F. / Zinc fingers and a green thumb : Manipulating gene expression in plants. In: Current Opinion in Plant Biology. 2003 ; Vol. 6, No. 2. pp. 163-168.
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