Zinc-catalyzed silylation of terminal alkynes

Ronald J. Rahaim, Jared T. Shaw

Research output: Contribution to journalArticle

32 Scopus citations

Abstract

(Chemical Equation Presented) A rapid and high-yielding silylation of terminal alkynes employing TMSOTf and catalytic quantities of Zn(OTf) 2 has been developed. The reaction works well for a variety of substrates including reactive esters. Fifteen examples with yields of >90% are reported.

Original languageEnglish (US)
Pages (from-to)2912-2915
Number of pages4
JournalJournal of Organic Chemistry
Volume73
Issue number7
DOIs
StatePublished - Apr 4 2008

ASJC Scopus subject areas

  • Organic Chemistry

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