Zinc is essential for the normal development and function of the nervous system. In humans, and depending on the developmental stage, zinc deficiency affects infant behavior, cognition, and motor performance [1-6]. In this regard, low plasma zinc values were found to be associated with altered cognition and emotional functioning in three rural communities of low-income 3- to 5-year-old children in the United States  and with pregnancy complications and altered child psychomotor development in a population from central Russia . Low plasma zinc concentrations are also correlated with the occurrence of inattentive symptoms in children with attention/hyperactivity disorder . Stressing the relevance of an adequate zinc nutrition for normal brain physiology, several studies have shown that zinc supplementation of undernourished children improves developmental quotients, activity patterns, and neuropsychological functions [2,3,6,10-12]. Given these data and the fact that the risk for zinc undernutrition is high throughout the world [13,14], the potential deleterious impact of zinc deficiency on brain development and function has to be considered of significant health concern in human populations.
|Original language||English (US)|
|Title of host publication||Micronutrients and Brain Health|
|Number of pages||13|
|State||Published - Jan 1 2009|
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