Abstract
Objective: This study is to identify predictors of loss to follow-up among adults with head injury. Study Design and Setting: A prospective cohort of 1,857 adults enrolled in the Medical Research Council (MRC) CRASH trial known to be alive 2 weeks after head injury. Six-month follow-up was defined as "overdue" if over 6 months late. Patient information collected at enrollment and after 14 days was used to predict overdue follow-up. A random two-thirds of the cohort was analyzed using logistic regression and binary recursive partitioning. The regression model and decision rule derived by recursive partitioning were evaluated using the remaining third. Results: Overdue follow-up was more likely in patients aged 25-34 years (odds ratio, 1.76; 95% confidence interval [CI] = 1.18-2.62), victims of assault (1.63; 1.09-2.45), patients independent after 2 weeks (1.79; 1.18-2.72) and patients for whom postcodes (2.36; 1.65-3.39), telephone numbers (1.82; 1.19-2.79) or general practitioners (1.67; 1.16-2.39) were unknown. Binary recursive partitioning specifically identified males aged younger than 43 years to be at risk. Conclusion: Successful follow-up in head-injury studies requires patients' postcodes and telephone numbers to be available. Young men remain at risk of becoming lost to follow-up, presenting a challenge for researchers aiming for complete data.
Original language | English (US) |
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Pages (from-to) | 417-424 |
Number of pages | 8 |
Journal | Journal of Clinical Epidemiology |
Volume | 60 |
Issue number | 4 |
DOIs | |
State | Published - Apr 2007 |
Keywords
- Clinical trial
- Follow-up
- Loss to follow-up
- Outcome assessment
- Risk factors
- Traumatic brain injury
ASJC Scopus subject areas
- Medicine(all)
- Public Health, Environmental and Occupational Health
- Epidemiology