Yeast mer1 mutants display reduced levels of meiotic recombination.

J. Engebrecht, G. S. Roeder

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Abstract

Mutations at the MER1 locus were identified in a search for meiotic mutants defective in chromosome segregation. mer1 strains show decreased levels of inter- and intrachromosomal meiotic recombination and produce inviable spores. The MER1 gene was cloned by complementation of the spore inviability phenotype. Strains carrying disruptions of the MER1 gene are mitotically viable. The epistatic relationships between MER1 and previously characterized meiotic genes are described.

Original languageEnglish (US)
Pages (from-to)237-247
Number of pages11
JournalGenetics
Volume121
Issue number2
StatePublished - Feb 1989
Externally publishedYes

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ASJC Scopus subject areas

  • Genetics
  • Genetics(clinical)

Cite this

Engebrecht, J., & Roeder, G. S. (1989). Yeast mer1 mutants display reduced levels of meiotic recombination. Genetics, 121(2), 237-247.