TY - JOUR
T1 - Y-Chromosomal Insights into Breeding History and Sire Line Genealogies of Arabian Horses
AU - Remer, Viktoria
AU - Bozlak, Elif
AU - Felkel, Sabine
AU - Radovic, Lara
AU - Rigler, Doris
AU - Grilz-Seger, Gertrud
AU - Stefaniuk-Szmukier, Monika
AU - Bugno-Poniewierska, Monika
AU - Brooks, Samantha
AU - Miller, Donald C.
AU - Antczak, Douglas F.
AU - Sadeghi, Raheleh
AU - Cothran, Gus
AU - Juras, Rytis
AU - Khanshour, Anas M.
AU - Rieder, Stefan
AU - Penedo, Maria C.
AU - Waiditschka, Gudrun
AU - Kalinkova, Liliya
AU - Kalashnikov, Valery V.
AU - Zaitsev, Alexander M.
AU - Almarzook, Saria
AU - Reißmann, Monika
AU - Brockmann, Gudrun A.
AU - Brem, Gottfried
AU - Wallner, Barbara
N1 - Funding Information:
Funding: This research was funded by the Innovation Fund of the Austrian Academy of Sciences (ÖAW), grant number IF_2015_17; the Austrian Federal Ministry of Agriculture, Forestry, Environment and Water Management DAFNE, grant number 101184; and with partial funding from the National Priorities Research Program (NPRP), grant 6-1303-4-023 from the Qatar National Research Fund (a member of Qatar Foundation). E.B. was funded by the Austrian Science Funds (FWF, W1225). Samples provided by the All-Russian Research Institute for Horse Breeding were obtained with the support of the Russian Science Foundation, Project Number 19-76-20058. D.F.A. is an Investigator of the Dorothy Russell Havemeyer Foundation, Inc.
Publisher Copyright:
© 2022 by the authors. Licensee MDPI, Basel, Switzerland.
PY - 2022/2
Y1 - 2022/2
N2 - The Y chromosome is a valuable genetic marker for studying the origin and influence of paternal lineages in populations. In this study, we conducted Y-chromosomal lineage-tracing in Arabian horses. First, we resolved a Y haplotype phylogeny based on the next generation sequencing data of 157 males from several breeds. Y-chromosomal haplotypes specific for Arabian horses were inferred by genotyping a collection of 145 males representing most Arabian sire lines that are active around the globe. These lines formed three discrete haplogroups, and the same haplogroups were detected in Arabian populations native to the Middle East. The Arabian haplotypes were clearly distinct from the ones detected in Akhal Tekes, Turkoman horses, and the progeny of two Thoroughbred foundation sires. However, a haplotype introduced into the English Thoroughbred by the stallion Byerley Turk (1680), was shared among Arabians, Turkomans, and Akhal Tekes, which opens a discussion about the historic connections between Oriental horse types. Furthermore, we genetically traced Arabian sire line breeding in the Western World over the past 200 years. This confirmed a strong selection for relatively few male lineages and uncovered incongruences to written pedigree records. Overall, we demonstrate how fine-scaled Y-analysis contributes to a better understanding of the historical development of horse breeds.
AB - The Y chromosome is a valuable genetic marker for studying the origin and influence of paternal lineages in populations. In this study, we conducted Y-chromosomal lineage-tracing in Arabian horses. First, we resolved a Y haplotype phylogeny based on the next generation sequencing data of 157 males from several breeds. Y-chromosomal haplotypes specific for Arabian horses were inferred by genotyping a collection of 145 males representing most Arabian sire lines that are active around the globe. These lines formed three discrete haplogroups, and the same haplogroups were detected in Arabian populations native to the Middle East. The Arabian haplotypes were clearly distinct from the ones detected in Akhal Tekes, Turkoman horses, and the progeny of two Thoroughbred foundation sires. However, a haplotype introduced into the English Thoroughbred by the stallion Byerley Turk (1680), was shared among Arabians, Turkomans, and Akhal Tekes, which opens a discussion about the historic connections between Oriental horse types. Furthermore, we genetically traced Arabian sire line breeding in the Western World over the past 200 years. This confirmed a strong selection for relatively few male lineages and uncovered incongruences to written pedigree records. Overall, we demonstrate how fine-scaled Y-analysis contributes to a better understanding of the historical development of horse breeds.
KW - Arabian horse
KW - Foundation sire
KW - Genotyping
KW - Haplotype
KW - Horse breeding
KW - Male genealogy
KW - Paternal lineage tracing
KW - Pedigree
KW - Y chromosome
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U2 - 10.3390/genes13020229
DO - 10.3390/genes13020229
M3 - Article
C2 - 35205275
AN - SCOPUS:85124094922
VL - 13
JO - Genes
JF - Genes
SN - 2073-4425
IS - 2
M1 - 229
ER -