Abstract
We present a hybrid imaging modality, x-ray luminescence optical tomography (XLOT), in which collimated x-ray beams are used to excite phosphor-based contrast agents. Images are reconstructed from the optical signals, using the known x-ray beam location and spatial extent aspriors. We demonstrate XLOT using phantom experiments with deep targets and show that the reconstructed signal varies by <12% when the depth changes from 4.2 to 7.7 mm. For simple source distributions, we find as few as two orthogonal projection measurements are sufficient for XLOT reconstruction.
Original language | English (US) |
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Pages (from-to) | 2339-2341 |
Number of pages | 3 |
Journal | Optics Letters |
Volume | 38 |
Issue number | 13 |
DOIs | |
State | Published - Jul 1 2013 |
ASJC Scopus subject areas
- Atomic and Molecular Physics, and Optics
- Medicine(all)