X-ray luminescence optical tomography imaging experimental studies

Changqing Li, Kun Di, Julien Bec, Simon R Cherry

Research output: Contribution to journalArticle

49 Citations (Scopus)

Abstract

We present a hybrid imaging modality, x-ray luminescence optical tomography (XLOT), in which collimated x-ray beams are used to excite phosphor-based contrast agents. Images are reconstructed from the optical signals, using the known x-ray beam location and spatial extent aspriors. We demonstrate XLOT using phantom experiments with deep targets and show that the reconstructed signal varies by <12% when the depth changes from 4.2 to 7.7 mm. For simple source distributions, we find as few as two orthogonal projection measurements are sufficient for XLOT reconstruction.

Original languageEnglish (US)
Pages (from-to)2339-2341
Number of pages3
JournalOptics Letters
Volume38
Issue number13
DOIs
StatePublished - Jul 1 2013

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Optical Tomography
Optical Imaging
Luminescence
tomography
X-Rays
luminescence
x rays
Multimodal Imaging
Contrast Media
phosphors
optical communication
projection

ASJC Scopus subject areas

  • Atomic and Molecular Physics, and Optics
  • Medicine(all)

Cite this

X-ray luminescence optical tomography imaging experimental studies. / Li, Changqing; Di, Kun; Bec, Julien; Cherry, Simon R.

In: Optics Letters, Vol. 38, No. 13, 01.07.2013, p. 2339-2341.

Research output: Contribution to journalArticle

Li, Changqing ; Di, Kun ; Bec, Julien ; Cherry, Simon R. / X-ray luminescence optical tomography imaging experimental studies. In: Optics Letters. 2013 ; Vol. 38, No. 13. pp. 2339-2341.
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