X-ray luminescence optical tomography imaging experimental studies

Changqing Li, Kun Di, Julien Bec, Simon R Cherry

Research output: Contribution to journalArticle

50 Scopus citations

Abstract

We present a hybrid imaging modality, x-ray luminescence optical tomography (XLOT), in which collimated x-ray beams are used to excite phosphor-based contrast agents. Images are reconstructed from the optical signals, using the known x-ray beam location and spatial extent aspriors. We demonstrate XLOT using phantom experiments with deep targets and show that the reconstructed signal varies by <12% when the depth changes from 4.2 to 7.7 mm. For simple source distributions, we find as few as two orthogonal projection measurements are sufficient for XLOT reconstruction.

Original languageEnglish (US)
Pages (from-to)2339-2341
Number of pages3
JournalOptics Letters
Volume38
Issue number13
DOIs
StatePublished - Jul 1 2013

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ASJC Scopus subject areas

  • Atomic and Molecular Physics, and Optics
  • Medicine(all)

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