Why Airway Gland Secretions Are Abnormally Sticky in Cystic Fibrosis, and Why Not Much Can Be Done About It

Research output: Contribution to journalArticlepeer-review

Abstract

In this issue of Developmental Cell, Xie et al. show that in cystic fibrosis, airway gland mucus gels form under conditions of high acidity and protein concentration. This causes them to be unusually stiff. This abnormal rheology cannot be corrected by changing pH or calcium levels in the bathing medium.

Original languageEnglish (US)
Pages (from-to)427-428
Number of pages2
JournalDevelopmental Cell
Volume54
Issue number4
DOIs
StatePublished - Aug 24 2020

ASJC Scopus subject areas

  • Molecular Biology
  • Biochemistry, Genetics and Molecular Biology(all)
  • Developmental Biology
  • Cell Biology

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