What's Wrong With My Mouse?

Behavioral Phenotyping of Transgenic and Knockout Mice: Second Edition

Research output: Book/ReportBook

453 Citations (Scopus)

Abstract

Dr. Jacqueline N. Crawley, author of the First and Second Editions of What's Wrong with My Mouse? Behavioral Phenotyping of Transgenic and Knockout Mice,continues to field calls and e-mails from molecular geneticists who ask: how do I run behavioral assays to find out what's wrong with my mouse? Turn to What's Wrong with My Mouse? to discover the wealth of mouse behavioral tasks and to get the guidance you need to select the best methods and necessary controls. Chapters are organized by behavioral domain, including measurements of general health, motor functions, sensory abilities, learning and memory, feeding and drinking, reproductive, social, emotional, and reward behaviors in mutant mice. Throughout the chapters, new behavioral tasks and new research discoveries have been added, bringing the Second Edition up to date with the latest science. In addition, the Second Edition includes two new chapters: "Neurodevelopment and Neurodegeneration" discusses mouse behavioral tasks relevant to neurodevelopmental diseases, such as mental retardation and autism, and to neurodegenerative diseases, such as Alzheimers, Parkinsons, Huntingtons, and amyotrophic lateral sclerosis. "Putting It All Together" recommends strategies for optimizing a battery of behavioral phenotyping tests to address your specific hypotheses about gene functions.

Original languageEnglish (US)
PublisherJohn Wiley & Sons, Inc.
Number of pages523
ISBN (Print)9780471471929
DOIs
StatePublished - Aug 24 2006
Externally publishedYes

Fingerprint

Knockout Mice
Transgenic Mice
Aptitude
Amyotrophic Lateral Sclerosis
Postal Service
Autistic Disorder
Reward
Intellectual Disability
Neurodegenerative Diseases
Drinking
Learning
Health
Research
Genes

ASJC Scopus subject areas

  • Neuroscience(all)

Cite this

What's Wrong With My Mouse? Behavioral Phenotyping of Transgenic and Knockout Mice: Second Edition. / Crawley, Jacqueline.

John Wiley & Sons, Inc., 2006. 523 p.

Research output: Book/ReportBook

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