What to do if the lymph nodes are positive

Christopher P Evans, D. A. Swanson

Research output: Contribution to journalArticle

7 Citations (Scopus)

Abstract

Lymph node metastases are common in patients with advanced bladder cancer. Survival rates have apparently improved from about 15% to 30% as management evolved from lymphadenectomy plus cystectomy to multimodal therapy, but investigators have not conclusively shown the benefit of adjuvant irradiation and/or chemotherapy. If clinical staging indicates nodal metastases, we recommend primary multiagent chemotherapy with subsequent exploratory laparotomy, lymphadenectomy, and possibly cystectomy for complete responders. Patients without clinical evidence of metastases undergo complete bilateral pelvic lymphadenectomy plus cystectomy if nodes are normal, or if grossly abnormal but resectable. Patients with nodal metastases may be candidates for adjuvant chemotherapy.

Original languageEnglish (US)
Pages (from-to)96-102
Number of pages7
JournalSeminars in Urologic Oncology
Volume14
Issue number2
StatePublished - 1996
Externally publishedYes

Fingerprint

Cystectomy
Lymph Node Excision
Lymph Nodes
Neoplasm Metastasis
Drug Therapy
Adjuvant Chemotherapy
Urinary Bladder Neoplasms
Laparotomy
Survival Rate
Research Personnel
Therapeutics

Keywords

  • bladder cancer
  • Lymph nodes
  • metastases

ASJC Scopus subject areas

  • Urology

Cite this

What to do if the lymph nodes are positive. / Evans, Christopher P; Swanson, D. A.

In: Seminars in Urologic Oncology, Vol. 14, No. 2, 1996, p. 96-102.

Research output: Contribution to journalArticle

Evans, CP & Swanson, DA 1996, 'What to do if the lymph nodes are positive', Seminars in Urologic Oncology, vol. 14, no. 2, pp. 96-102.
Evans, Christopher P ; Swanson, D. A. / What to do if the lymph nodes are positive. In: Seminars in Urologic Oncology. 1996 ; Vol. 14, No. 2. pp. 96-102.
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