West Nile virus infection in tree squirrels (rodentia: Sciuridae) in California, 2004-2005

Kerry A. Padgett, William Reisen, Nicole Kahl-Purcell, Ying Fang, Barbara Cahoon-Young, Ryan Carney, Nancy Anderson, Lynda Zucca, Leslie Woods, Stan Husted, Vicki L. Kramer

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

West Nile virus (WNV) transmission generally involves a mosquito vector and an avian reservoir host, with mammals as incidental hosts. Although most mammalian WNV infections cause low or no morbidity or mortality, tree squirrels are susceptible to WNV-associated neurologic disease with infection prevalence comparable to that in dead birds. Positive species included fox squirrel (Sciurus niger), western gray squirrel (S. griseus), and eastern gray squirrel (S. carolinensis). Kidney tissue (dissected and swabbed) and oropharyngeal (oral) swab samples from tree squirrels, submitted by California vector control and rehabilitation agencies, were tested by reverse transcription-polymerase chain reaction; cycle threshold values were similar for all three samples, ranging from 21.9 to 26.5. Kidney tissue was more sensitive than oral swabs for detecting WNV in squirrels. Three of 36 live neurologic tree squirrels had viremia approximately 5 log10 plaqueforming units/ml or greater, similar to WNV-infected birds. Tree squirrels are useful in WNV surveillance and provide localized evidence of WNV transmission to mammals.

Original languageEnglish (US)
Pages (from-to)35-39
Number of pages5
JournalJournal of Wildlife Rehabilitation
Volume29
Issue number2-3
StatePublished - 2008

Fingerprint

Sciuridae
West Nile virus
squirrels
Virus Diseases
Rodentia
Sciurus carolinensis
infection
virus transmission
Birds
Mammals
kidneys
mammals
disease reservoirs
nervous system diseases
vector control
Kidney
birds
viremia
tree mortality
foxes

Keywords

  • Disease surveillance
  • Mammal transmission
  • Tree squirrel
  • West Nile virus

ASJC Scopus subject areas

  • Animal Science and Zoology
  • veterinary(all)

Cite this

Padgett, K. A., Reisen, W., Kahl-Purcell, N., Fang, Y., Cahoon-Young, B., Carney, R., ... Kramer, V. L. (2008). West Nile virus infection in tree squirrels (rodentia: Sciuridae) in California, 2004-2005. Journal of Wildlife Rehabilitation, 29(2-3), 35-39.

West Nile virus infection in tree squirrels (rodentia : Sciuridae) in California, 2004-2005. / Padgett, Kerry A.; Reisen, William; Kahl-Purcell, Nicole; Fang, Ying; Cahoon-Young, Barbara; Carney, Ryan; Anderson, Nancy; Zucca, Lynda; Woods, Leslie; Husted, Stan; Kramer, Vicki L.

In: Journal of Wildlife Rehabilitation, Vol. 29, No. 2-3, 2008, p. 35-39.

Research output: Contribution to journalArticle

Padgett, KA, Reisen, W, Kahl-Purcell, N, Fang, Y, Cahoon-Young, B, Carney, R, Anderson, N, Zucca, L, Woods, L, Husted, S & Kramer, VL 2008, 'West Nile virus infection in tree squirrels (rodentia: Sciuridae) in California, 2004-2005', Journal of Wildlife Rehabilitation, vol. 29, no. 2-3, pp. 35-39.
Padgett KA, Reisen W, Kahl-Purcell N, Fang Y, Cahoon-Young B, Carney R et al. West Nile virus infection in tree squirrels (rodentia: Sciuridae) in California, 2004-2005. Journal of Wildlife Rehabilitation. 2008;29(2-3):35-39.
Padgett, Kerry A. ; Reisen, William ; Kahl-Purcell, Nicole ; Fang, Ying ; Cahoon-Young, Barbara ; Carney, Ryan ; Anderson, Nancy ; Zucca, Lynda ; Woods, Leslie ; Husted, Stan ; Kramer, Vicki L. / West Nile virus infection in tree squirrels (rodentia : Sciuridae) in California, 2004-2005. In: Journal of Wildlife Rehabilitation. 2008 ; Vol. 29, No. 2-3. pp. 35-39.
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