West Nile viral infection of equids

J. Angenvoort, Aaron Brault, R. A. Bowen, M. H. Groschup

Research output: Contribution to journalArticle

26 Citations (Scopus)

Abstract

West Nile virus (WNV) is a flavivirus transmitted between certain species of birds and mosquito vectors. Tangential infections of equids and subsequent equine epizootics have occurred historically. Although the attack rate has been estimated to be below 10%, mortality rates can approach 50% in horses that present clinical disease. Symptoms are most commonly presenting in the form of encephalitis with ataxia as well as limb weakness, recumbency and muscle fasciculation. The most effective strategy for prevention of equine disease is proper vaccination with one of the numerous commercially available vaccines available in North America or the European Union. Recently, WNV has been increasingly associated with equine epizootics resulting from novel non-lineage-1a viruses in expanding geographic areas. However, specific experimental data on the virulence of these novel virus strains is lacking and questions remain as to the etiology of the expanded epizootics: whether it be a function of inherent virulence or ecological and/or climactic factors that could precipitate the altered epidemiological patterns observed.

Original languageEnglish (US)
Pages (from-to)168-180
Number of pages13
JournalVeterinary Microbiology
Volume167
Issue number1-2
DOIs
StatePublished - Nov 29 2013
Externally publishedYes

Fingerprint

Virus Diseases
Horses
West Nile virus
horses
Virulence
virulence
Horse Diseases
infection
Fasciculation
Viruses
Flavivirus
viruses
horse diseases
Muscle Weakness
European Union
Encephalitis
Ataxia
encephalitis
North America
limbs (animal)

Keywords

  • Equids
  • Flavivirus
  • Horses
  • West Nile virus

ASJC Scopus subject areas

  • Microbiology
  • veterinary(all)

Cite this

Angenvoort, J., Brault, A., Bowen, R. A., & Groschup, M. H. (2013). West Nile viral infection of equids. Veterinary Microbiology, 167(1-2), 168-180. https://doi.org/10.1016/j.vetmic.2013.08.013

West Nile viral infection of equids. / Angenvoort, J.; Brault, Aaron; Bowen, R. A.; Groschup, M. H.

In: Veterinary Microbiology, Vol. 167, No. 1-2, 29.11.2013, p. 168-180.

Research output: Contribution to journalArticle

Angenvoort, J, Brault, A, Bowen, RA & Groschup, MH 2013, 'West Nile viral infection of equids', Veterinary Microbiology, vol. 167, no. 1-2, pp. 168-180. https://doi.org/10.1016/j.vetmic.2013.08.013
Angenvoort, J. ; Brault, Aaron ; Bowen, R. A. ; Groschup, M. H. / West Nile viral infection of equids. In: Veterinary Microbiology. 2013 ; Vol. 167, No. 1-2. pp. 168-180.
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