Warning! Nearby construction can profoundly affect your experiments

Mary F. Dallman, Susan F. Akana, M. E. Bell, Seema Bhatnagar, SuJean J. Choi, Alan Chu, Francisca Gomez, Kevin Laugero, Liza Soriano, Victor Viau

Research output: Contribution to journalArticle

28 Scopus citations

Abstract

This is meant to alert people to potentially major effects of construction projects on research results. Because we study the effects of stress on regulation of ACTH and corticosterone secretion and of serotonin receptors and stress on energy balance, we serve as an early warning system when things go awry. Most of our experiments include taking daily, or twice daily, measurements of rat or mouse weights and food intake as well as stress hormone levels. We are highly sensitized to environmental disruption and we've shown previously the effects of construction on stress hormones (1). However, we did not anticipate the change and disruption in energy balance that may occur in response to environmental perturbation. We provide two examples of these, below.

Original languageEnglish (US)
Pages (from-to)111-113
Number of pages3
JournalEndocrine
Volume11
Issue number2
StatePublished - 1999
Externally publishedYes

Keywords

  • Body weight
  • Food intake
  • Phenotypic expression
  • Rhythms

ASJC Scopus subject areas

  • Endocrinology

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    Dallman, M. F., Akana, S. F., Bell, M. E., Bhatnagar, S., Choi, S. J., Chu, A., Gomez, F., Laugero, K., Soriano, L., & Viau, V. (1999). Warning! Nearby construction can profoundly affect your experiments. Endocrine, 11(2), 111-113.