Von Hippel-Lindau disease and erythrocytosis: Radioimmunoassay of erythropoietin in cyst fluid from a brainstem hemangioblastoma

Jonathan C. Horton, Griffith R. Harsh IV, James W. Fisher, William F. Hoyt

Research output: Contribution to journalArticlepeer-review

Abstract

A 59-year-old woman with von Hippel-Lindau disease developed erythrocytosis and a recurrent intracranial hemangioblastoma. Radioimmunoassay showed an elevated level of erythropoietin in her serum. Cyst fluid from the tumor also contained erythropoietin, concentrated a thousandfold relative to the serum level. Production of erythropoietin by hemangioblastomas may explain the erythrocytosis present in some patients with von Hippel-Lindau disease.

Original languageEnglish (US)
Pages (from-to)753-754
Number of pages2
JournalNeurology
Volume41
Issue number5
DOIs
StatePublished - May 1991
Externally publishedYes

ASJC Scopus subject areas

  • Clinical Neurology

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