Vitamin B12 deficiency, tumor necrosis factor-α, and epidermal growth factor: A novel function for vitamin B12?

Joshua W. Miller

Research output: Contribution to journalArticle

20 Citations (Scopus)

Abstract

Vitamin B12 deficiency was recently shown to be associated with elevated levels of tumor necrosis factor-α and decreased levels of epidermal growth factor in both rats and humans. These findings suggest a novel pathogenetic mechanism underlying the neuropathology of vitamin B12 deficiency. They may also explain putative relationships between vitamin B12 deficiency and certain disorders, including Alzheimer's disease, rheumatoid arthritis, and AIDS.

Original languageEnglish (US)
Pages (from-to)142-144
Number of pages3
JournalNutrition Reviews
Volume60
Issue number5 I
DOIs
StatePublished - 2002
Externally publishedYes

Fingerprint

Vitamin B 12 Deficiency
tumor necrosis factors
epidermal growth factor
vitamin B12
Vitamin B 12
Epidermal Growth Factor
Tumor Necrosis Factor-alpha
neuropathology
rheumatoid arthritis
Alzheimer disease
Rheumatoid Arthritis
Alzheimer Disease
Acquired Immunodeficiency Syndrome
rats

Keywords

  • AIDS
  • Alzheimer's
  • Epidermal growth factor
  • Rheumatoid arthritis
  • Tumor necrosis factor-α
  • Vitamin B deficiency

ASJC Scopus subject areas

  • Medicine (miscellaneous)
  • Food Science

Cite this

Vitamin B12 deficiency, tumor necrosis factor-α, and epidermal growth factor : A novel function for vitamin B12? / Miller, Joshua W.

In: Nutrition Reviews, Vol. 60, No. 5 I, 2002, p. 142-144.

Research output: Contribution to journalArticle

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