Vitamin B12 deficiency presenting as acute ataxia

John Ross Crawford, Daphne Say

Research output: Contribution to journalArticle

9 Citations (Scopus)

Abstract

A previously healthy 7-year-old Caucasian boy was hospitalised for evaluation of acute ataxia and failure to thrive, initially suspicious for an intracranial mass. Weight and body mass index were below the third percentile and he demonstrated loss of joint position and vibratory sense on examination. Laboratory studies revealed megaloblastic anaemia while an initial MRI of the brain showed no evidence of mass lesions or other abnormalities. A dietary history revealed the child subscribed to a restrictive vegan diet with little to no intake of animal products or other fortified foods. The child was diagnosed with presumed vitamin B12 deficiency and was treated with intramuscular B12 injections. Neurological symptoms resolved promptly within several days after starting therapy. This case underlines the importance of assessing nutritional status in the evaluation of neurological dysfunction in the pediatric patient.

Original languageEnglish (US)
Article number008840
JournalBMJ Case Reports
DOIs
StatePublished - May 13 2013
Externally publishedYes

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Vitamin B 12 Deficiency
Ataxia
Fortified Food
Megaloblastic Anemia
Proprioception
Failure to Thrive
Intramuscular Injections
Nutritional Status
Body Mass Index
Joints
Pediatrics
Weights and Measures
Brain
Therapeutics
Vegan Diet

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Vitamin B12 deficiency presenting as acute ataxia. / Crawford, John Ross; Say, Daphne.

In: BMJ Case Reports, 13.05.2013.

Research output: Contribution to journalArticle

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