Visualizing the immune response to pathogens

Aparna Srinivasan, Stephen J Mcsorley

Research output: Contribution to journalArticle

14 Scopus citations

Abstract

Advances in immune visualization have enabled the physical tracking of immune responses in vivo. The adaptation of such technology to models of infectious disease holds the promise of a more detailed analysis of host-pathogen interactions in a natural setting. However, the visualization of pathogen-specific immune responses in vivo confronts challenges that are inherent to the study of infectious disease systems. Recent attempts to track pathogen-specific immune responses in vivo validate the usefulness and underline the complexity of this experimental strategy.

Original languageEnglish (US)
Pages (from-to)494-498
Number of pages5
JournalCurrent Opinion in Immunology
Volume16
Issue number4
DOIs
StatePublished - Aug 2004
Externally publishedYes

Keywords

  • antigen-presenting cell
  • APC
  • T-cell receptor
  • TCR

ASJC Scopus subject areas

  • Immunology and Allergy
  • Immunology

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