Abstract
Advances in immune visualization have enabled the physical tracking of immune responses in vivo. The adaptation of such technology to models of infectious disease holds the promise of a more detailed analysis of host-pathogen interactions in a natural setting. However, the visualization of pathogen-specific immune responses in vivo confronts challenges that are inherent to the study of infectious disease systems. Recent attempts to track pathogen-specific immune responses in vivo validate the usefulness and underline the complexity of this experimental strategy.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 494-498 |
| Number of pages | 5 |
| Journal | Current Opinion in Immunology |
| Volume | 16 |
| Issue number | 4 |
| DOIs | |
| State | Published - Aug 2004 |
| Externally published | Yes |
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Keywords
- antigen-presenting cell
- APC
- T-cell receptor
- TCR
ASJC Scopus subject areas
- Immunology and Allergy
- Immunology
Cite this
Visualizing the immune response to pathogens. / Srinivasan, Aparna; Mcsorley, Stephen J.
In: Current Opinion in Immunology, Vol. 16, No. 4, 08.2004, p. 494-498.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Visualizing the immune response to pathogens
AU - Srinivasan, Aparna
AU - Mcsorley, Stephen J
PY - 2004/8
Y1 - 2004/8
N2 - Advances in immune visualization have enabled the physical tracking of immune responses in vivo. The adaptation of such technology to models of infectious disease holds the promise of a more detailed analysis of host-pathogen interactions in a natural setting. However, the visualization of pathogen-specific immune responses in vivo confronts challenges that are inherent to the study of infectious disease systems. Recent attempts to track pathogen-specific immune responses in vivo validate the usefulness and underline the complexity of this experimental strategy.
AB - Advances in immune visualization have enabled the physical tracking of immune responses in vivo. The adaptation of such technology to models of infectious disease holds the promise of a more detailed analysis of host-pathogen interactions in a natural setting. However, the visualization of pathogen-specific immune responses in vivo confronts challenges that are inherent to the study of infectious disease systems. Recent attempts to track pathogen-specific immune responses in vivo validate the usefulness and underline the complexity of this experimental strategy.
KW - antigen-presenting cell
KW - APC
KW - T-cell receptor
KW - TCR
UR - http://www.scopus.com/inward/record.url?scp=3042815930&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=3042815930&partnerID=8YFLogxK
U2 - 10.1016/j.coi.2004.05.001
DO - 10.1016/j.coi.2004.05.001
M3 - Article
VL - 16
SP - 494
EP - 498
JO - Current Opinion in Immunology
JF - Current Opinion in Immunology
SN - 0952-7915
IS - 4
ER -