Visualizing the immune response to pathogens

Aparna Srinivasan; Stephen J Mcsorley

doi:10.1016/j.coi.2004.05.001

Visualizing the immune response to pathogens

Aparna Srinivasan, Stephen J Mcsorley

Research output: Contribution to journal › Article › peer-review

14 Scopus citations

Abstract

Advances in immune visualization have enabled the physical tracking of immune responses in vivo. The adaptation of such technology to models of infectious disease holds the promise of a more detailed analysis of host-pathogen interactions in a natural setting. However, the visualization of pathogen-specific immune responses in vivo confronts challenges that are inherent to the study of infectious disease systems. Recent attempts to track pathogen-specific immune responses in vivo validate the usefulness and underline the complexity of this experimental strategy.

Original language	English (US)
Pages (from-to)	494-498
Number of pages	5
Journal	Current Opinion in Immunology
Volume	16
Issue number	4
DOIs	https://doi.org/10.1016/j.coi.2004.05.001
State	Published - Aug 2004
Externally published	Yes

Keywords

antigen-presenting cell
APC
T-cell receptor
TCR

ASJC Scopus subject areas

Immunology and Allergy
Immunology

Access to Document

10.1016/j.coi.2004.05.001

Cite this

@article{749ca6bbf6db49c58c928d4c923ea660,

title = "Visualizing the immune response to pathogens",

abstract = "Advances in immune visualization have enabled the physical tracking of immune responses in vivo. The adaptation of such technology to models of infectious disease holds the promise of a more detailed analysis of host-pathogen interactions in a natural setting. However, the visualization of pathogen-specific immune responses in vivo confronts challenges that are inherent to the study of infectious disease systems. Recent attempts to track pathogen-specific immune responses in vivo validate the usefulness and underline the complexity of this experimental strategy.",

keywords = "antigen-presenting cell, APC, T-cell receptor, TCR",

author = "Aparna Srinivasan and Mcsorley, {Stephen J}",

year = "2004",

month = aug,

doi = "10.1016/j.coi.2004.05.001",

language = "English (US)",

volume = "16",

pages = "494--498",

journal = "Current Opinion in Immunology",

issn = "0952-7915",

publisher = "Elsevier Limited",

number = "4",

}

TY - JOUR

T1 - Visualizing the immune response to pathogens

AU - Srinivasan, Aparna

AU - Mcsorley, Stephen J

PY - 2004/8

Y1 - 2004/8

N2 - Advances in immune visualization have enabled the physical tracking of immune responses in vivo. The adaptation of such technology to models of infectious disease holds the promise of a more detailed analysis of host-pathogen interactions in a natural setting. However, the visualization of pathogen-specific immune responses in vivo confronts challenges that are inherent to the study of infectious disease systems. Recent attempts to track pathogen-specific immune responses in vivo validate the usefulness and underline the complexity of this experimental strategy.

AB - Advances in immune visualization have enabled the physical tracking of immune responses in vivo. The adaptation of such technology to models of infectious disease holds the promise of a more detailed analysis of host-pathogen interactions in a natural setting. However, the visualization of pathogen-specific immune responses in vivo confronts challenges that are inherent to the study of infectious disease systems. Recent attempts to track pathogen-specific immune responses in vivo validate the usefulness and underline the complexity of this experimental strategy.

KW - antigen-presenting cell

KW - APC

KW - T-cell receptor

KW - TCR

UR - http://www.scopus.com/inward/record.url?scp=3042815930&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=3042815930&partnerID=8YFLogxK

U2 - 10.1016/j.coi.2004.05.001

DO - 10.1016/j.coi.2004.05.001

M3 - Article

C2 - 15245745

AN - SCOPUS:3042815930

VL - 16

SP - 494

EP - 498

JO - Current Opinion in Immunology

JF - Current Opinion in Immunology

SN - 0952-7915

IS - 4

ER -

Visualizing the immune response to pathogens

Abstract

Keywords

ASJC Scopus subject areas

Access to Document

Other files and links

Fingerprint

Cite this