Abstract
We evaluate methods to visualize human retinal micro-circulation in vivo by standard intensity-based optical coherence tomography (OCT), speckle-variance optical coherence tomography (svOCT), and phase-variance optical coherence tomography (pvOCT). En face projection views created from the same volumetric data set of the human retina using all three data processing methods are created and compared. Additionally we used support vector machine (SVM) based semi-automatic segmentation to generate en face projection views of individual retinal layers. The layers include: first, the whole inner retina (from the nerve fiber layer to the outer nuclear layer), and second, from the ganglion cell layer to the outer nuclear layer. Finally, we compare the retinal vasculature images processed from the three OCT techniques and fluorescein angiography (FA).
Original language | English (US) |
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Title of host publication | Progress in Biomedical Optics and Imaging - Proceedings of SPIE |
Publisher | SPIE |
Volume | 8213 |
ISBN (Print) | 9780819488565 |
DOIs | |
State | Published - 2012 |
Event | Optical Coherence Tomography and Coherence Domain Optical Methods in Biomedicine XVI - San Francisco, CA, United States Duration: Jan 23 2012 → Jan 25 2012 |
Other
Other | Optical Coherence Tomography and Coherence Domain Optical Methods in Biomedicine XVI |
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Country | United States |
City | San Francisco, CA |
Period | 1/23/12 → 1/25/12 |
Keywords
- Imaging system
- Medical optics instrumentation
- Optical coherence tomography
- Phase contrast technique
ASJC Scopus subject areas
- Atomic and Molecular Physics, and Optics
- Electronic, Optical and Magnetic Materials
- Biomaterials
- Radiology Nuclear Medicine and imaging