Visual recognition memory and auditory brainstem response in infant rhesus monkeys exposed perinatally to environmental tobacco smoke

Mari S. Golub, Theodore A. Slotkin, Alice F Tarantal, Kent E Pinkerton

Research output: Contribution to journalArticle

18 Citations (Scopus)

Abstract

The impact of perinatal exposure to environmental tobacco smoke (ETS) on cognitive development is controversial. We exposed rhesus monkeys to ETS or filtered air (5 animals per group) beginning in utero on day 50 of pregnancy and continuing throughout postnatal testing. In infancy, we evaluated both groups for visual recognition memory and auditory function (auditory brainstem response). The ETS group showed significantly less novelty preference in the visual recognition task whereas no effects on auditory function were detected. These preliminary results support the view that perinatal ETS exposure has adverse effects on cognitive function and indicate further that rhesus monkeys may provide a valuable nonhuman primate model for investigating this link.

Original languageEnglish (US)
Pages (from-to)102-106
Number of pages5
JournalBrain Research
Volume1151
Issue number1
DOIs
StatePublished - Sep 4 2007

Fingerprint

Brain Stem Auditory Evoked Potentials
Macaca mulatta
Smoke
Tobacco
Environmental Exposure
Cognition
Primates
Air
Pregnancy
Recognition (Psychology)

Keywords

  • Behavior
  • Infant
  • Monkey
  • Perinatal
  • Smoking
  • Tobacco

ASJC Scopus subject areas

  • Neuroscience(all)
  • Clinical Neurology
  • Developmental Biology
  • Molecular Biology

Cite this

Visual recognition memory and auditory brainstem response in infant rhesus monkeys exposed perinatally to environmental tobacco smoke. / Golub, Mari S.; Slotkin, Theodore A.; Tarantal, Alice F; Pinkerton, Kent E.

In: Brain Research, Vol. 1151, No. 1, 04.09.2007, p. 102-106.

Research output: Contribution to journalArticle

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