Visual recognition memory and auditory brainstem response in infant rhesus monkeys exposed perinatally to environmental tobacco smoke

Mari S. Golub; Theodore A. Slotkin; Alice F Tarantal; Kent E Pinkerton

doi:10.1016/j.brainres.2007.03.001

Visual recognition memory and auditory brainstem response in infant rhesus monkeys exposed perinatally to environmental tobacco smoke

Mari S. Golub, Theodore A. Slotkin, Alice F Tarantal, Kent E Pinkerton

Research output: Contribution to journal › Article › peer-review

20 Scopus citations

Abstract

The impact of perinatal exposure to environmental tobacco smoke (ETS) on cognitive development is controversial. We exposed rhesus monkeys to ETS or filtered air (5 animals per group) beginning in utero on day 50 of pregnancy and continuing throughout postnatal testing. In infancy, we evaluated both groups for visual recognition memory and auditory function (auditory brainstem response). The ETS group showed significantly less novelty preference in the visual recognition task whereas no effects on auditory function were detected. These preliminary results support the view that perinatal ETS exposure has adverse effects on cognitive function and indicate further that rhesus monkeys may provide a valuable nonhuman primate model for investigating this link.

Original language	English (US)
Pages (from-to)	102-106
Number of pages	5
Journal	Brain Research
Volume	1151
Issue number	1
DOIs	https://doi.org/10.1016/j.brainres.2007.03.001
State	Published - Sep 4 2007

Keywords

Behavior
Infant
Monkey
Perinatal
Smoking
Tobacco

ASJC Scopus subject areas

Neuroscience(all)
Clinical Neurology
Developmental Biology
Molecular Biology

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10.1016/j.brainres.2007.03.001

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abstract = "The impact of perinatal exposure to environmental tobacco smoke (ETS) on cognitive development is controversial. We exposed rhesus monkeys to ETS or filtered air (5 animals per group) beginning in utero on day 50 of pregnancy and continuing throughout postnatal testing. In infancy, we evaluated both groups for visual recognition memory and auditory function (auditory brainstem response). The ETS group showed significantly less novelty preference in the visual recognition task whereas no effects on auditory function were detected. These preliminary results support the view that perinatal ETS exposure has adverse effects on cognitive function and indicate further that rhesus monkeys may provide a valuable nonhuman primate model for investigating this link.",

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AU - Pinkerton, Kent E

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Visual recognition memory and auditory brainstem response in infant rhesus monkeys exposed perinatally to environmental tobacco smoke

Abstract

Keywords

ASJC Scopus subject areas

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