Abstract
Purpose: To determine the macular morphologic features that correlate best with visual outcome in eyes with surgically closed idiopathic macular hole. Methods: Transversal observational case series of 24 eyes (22 subjects) imaged postoperatively using high-resolution Fourier domain optical coherence tomography (FDOCT). Total and inner macular volume for central 3 mm area, central foveal thickness, and size of foveal inner segment-outer segment junction abnormality were correlated with bestcorrected visual acuity. Microperimetry (MP-1) test was performed in a subset of 18 eyes. Results: Mean postoperative best-corrected visual acuity was 20/36 (range, 20/25-20/ 70). Postoperative follow-up mean was 32.97 ± 24.68 months (range, 5-96 months). Eighteen eyes underwent internal limiting membrane (ILM) peeling. Among FD-OCT parameters, logarithm of the minimum angle of resolution best-corrected visual acuity and mean total microperimetry-1 sensitivity correlated best with inner macular volume in all eyes and ILMpeeled eyes (P < 0.05). Macular surface irregularities were noted in 12 eyes (66.7%) with ILM peeling but in none of the non-ILM-peeled eyes (P = 0.02). No significant correlation was found between microperimetry-1 sensitivity and other FD-OCT parameters. Conclusion: Because inner macular volume strongly correlated with visual outcome in eyes with surgically closed macular hole, the possible effect of ILM peeling on visual outcome needs to be further investigated.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 2085-2095 |
| Number of pages | 11 |
| Journal | Retina |
| Volume | 32 |
| Issue number | 10 |
| DOIs | |
| State | Published - Nov 2012 |
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Keywords
- Central foveal thickness
- Fourier domain optical coherence tomography
- Foveal photoreceptor abnormality
- Internal limiting membrane
- Macular hole
- Macular volume
- Microperimetry
ASJC Scopus subject areas
- Ophthalmology
Cite this
Visual outcome correlates with inner macular volume in eyes with surgically closed macular hole. / Pilli, Suman; Zawadzki, Robert; Werner, John S; Park, Susanna Soon Chun.
In: Retina, Vol. 32, No. 10, 11.2012, p. 2085-2095.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Visual outcome correlates with inner macular volume in eyes with surgically closed macular hole
AU - Pilli, Suman
AU - Zawadzki, Robert
AU - Werner, John S
AU - Park, Susanna Soon Chun
PY - 2012/11
Y1 - 2012/11
N2 - Purpose: To determine the macular morphologic features that correlate best with visual outcome in eyes with surgically closed idiopathic macular hole. Methods: Transversal observational case series of 24 eyes (22 subjects) imaged postoperatively using high-resolution Fourier domain optical coherence tomography (FDOCT). Total and inner macular volume for central 3 mm area, central foveal thickness, and size of foveal inner segment-outer segment junction abnormality were correlated with bestcorrected visual acuity. Microperimetry (MP-1) test was performed in a subset of 18 eyes. Results: Mean postoperative best-corrected visual acuity was 20/36 (range, 20/25-20/ 70). Postoperative follow-up mean was 32.97 ± 24.68 months (range, 5-96 months). Eighteen eyes underwent internal limiting membrane (ILM) peeling. Among FD-OCT parameters, logarithm of the minimum angle of resolution best-corrected visual acuity and mean total microperimetry-1 sensitivity correlated best with inner macular volume in all eyes and ILMpeeled eyes (P < 0.05). Macular surface irregularities were noted in 12 eyes (66.7%) with ILM peeling but in none of the non-ILM-peeled eyes (P = 0.02). No significant correlation was found between microperimetry-1 sensitivity and other FD-OCT parameters. Conclusion: Because inner macular volume strongly correlated with visual outcome in eyes with surgically closed macular hole, the possible effect of ILM peeling on visual outcome needs to be further investigated.
AB - Purpose: To determine the macular morphologic features that correlate best with visual outcome in eyes with surgically closed idiopathic macular hole. Methods: Transversal observational case series of 24 eyes (22 subjects) imaged postoperatively using high-resolution Fourier domain optical coherence tomography (FDOCT). Total and inner macular volume for central 3 mm area, central foveal thickness, and size of foveal inner segment-outer segment junction abnormality were correlated with bestcorrected visual acuity. Microperimetry (MP-1) test was performed in a subset of 18 eyes. Results: Mean postoperative best-corrected visual acuity was 20/36 (range, 20/25-20/ 70). Postoperative follow-up mean was 32.97 ± 24.68 months (range, 5-96 months). Eighteen eyes underwent internal limiting membrane (ILM) peeling. Among FD-OCT parameters, logarithm of the minimum angle of resolution best-corrected visual acuity and mean total microperimetry-1 sensitivity correlated best with inner macular volume in all eyes and ILMpeeled eyes (P < 0.05). Macular surface irregularities were noted in 12 eyes (66.7%) with ILM peeling but in none of the non-ILM-peeled eyes (P = 0.02). No significant correlation was found between microperimetry-1 sensitivity and other FD-OCT parameters. Conclusion: Because inner macular volume strongly correlated with visual outcome in eyes with surgically closed macular hole, the possible effect of ILM peeling on visual outcome needs to be further investigated.
KW - Central foveal thickness
KW - Fourier domain optical coherence tomography
KW - Foveal photoreceptor abnormality
KW - Internal limiting membrane
KW - Macular hole
KW - Macular volume
KW - Microperimetry
UR - http://www.scopus.com/inward/record.url?scp=84871332006&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84871332006&partnerID=8YFLogxK
U2 - 10.1097/IAE.0b013e31825c1c0c
DO - 10.1097/IAE.0b013e31825c1c0c
M3 - Article
C2 - 23095727
AN - SCOPUS:84871332006
VL - 32
SP - 2085
EP - 2095
JO - Retina
JF - Retina
SN - 0275-004X
IS - 10
ER -