Visual outcome correlates with inner macular volume in eyes with surgically closed macular hole

Research output: Contribution to journalArticle

16 Citations (Scopus)

Abstract

Purpose: To determine the macular morphologic features that correlate best with visual outcome in eyes with surgically closed idiopathic macular hole. Methods: Transversal observational case series of 24 eyes (22 subjects) imaged postoperatively using high-resolution Fourier domain optical coherence tomography (FDOCT). Total and inner macular volume for central 3 mm area, central foveal thickness, and size of foveal inner segment-outer segment junction abnormality were correlated with bestcorrected visual acuity. Microperimetry (MP-1) test was performed in a subset of 18 eyes. Results: Mean postoperative best-corrected visual acuity was 20/36 (range, 20/25-20/ 70). Postoperative follow-up mean was 32.97 ± 24.68 months (range, 5-96 months). Eighteen eyes underwent internal limiting membrane (ILM) peeling. Among FD-OCT parameters, logarithm of the minimum angle of resolution best-corrected visual acuity and mean total microperimetry-1 sensitivity correlated best with inner macular volume in all eyes and ILMpeeled eyes (P < 0.05). Macular surface irregularities were noted in 12 eyes (66.7%) with ILM peeling but in none of the non-ILM-peeled eyes (P = 0.02). No significant correlation was found between microperimetry-1 sensitivity and other FD-OCT parameters. Conclusion: Because inner macular volume strongly correlated with visual outcome in eyes with surgically closed macular hole, the possible effect of ILM peeling on visual outcome needs to be further investigated.

Original languageEnglish (US)
Pages (from-to)2085-2095
Number of pages11
JournalRetina
Volume32
Issue number10
DOIs
StatePublished - Nov 2012

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Retinal Perforations
Visual Acuity
Membranes
Optical Coherence Tomography

Keywords

  • Central foveal thickness
  • Fourier domain optical coherence tomography
  • Foveal photoreceptor abnormality
  • Internal limiting membrane
  • Macular hole
  • Macular volume
  • Microperimetry

ASJC Scopus subject areas

  • Ophthalmology

Cite this

Visual outcome correlates with inner macular volume in eyes with surgically closed macular hole. / Pilli, Suman; Zawadzki, Robert; Werner, John S; Park, Susanna Soon Chun.

In: Retina, Vol. 32, No. 10, 11.2012, p. 2085-2095.

Research output: Contribution to journalArticle

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