Visual insignificance of the foveal pit: Reassessment of foveal hypoplasia as fovea plana

Michael F. Marmor, Stacey S. Choi, Robert Zawadzki, John S Werner

Research output: Contribution to journalArticle

118 Citations (Scopus)

Abstract

Objectives: To elucidate the visual significance of the foveal pit by measuring foveal architecture and function and to reassess use of the term foveal hypoplasia (as visual acuity can vary among patients who lack a pit). Methods: We describe 4 patients who lack a foveal pit. Visual acuities ranged from 20/20 to 20/50. Stratus and Cirrus (Carl Zeiss Meditec, Dublin, California) optical coherence tomographs (OCXs) and multifocal electroretinograms were obtained. High-resolution retinal imaging on 2 of the participants was obtained by using a high-resolution Fourier-domain OCT and an adaptive optics flood-illuminated fundus camera. Results: No participants had a visible foveal pit with conventional OCT. Central widening of the outer nuclear layer and lengthening of cone outer segments were seen with high-resolution Fourier-domain OCT. Adaptive optics imaging showed normal cone diameters in the central 1° to 2°. Central multifocal electroretinogram responses were normal. Conclusions: We show that a foveal pit is not required for foveal cone specialization, anatomically or functionally. This helps to explain the potential for good acuity in the absence of a pit and raises questions about the visual role of the foveal pit. Because the term foveal hypoplasia commonly carries a negative functional implication, it may be more proper to call the anatomic lack of a pit fovea plana.

Original languageEnglish (US)
Pages (from-to)907-913
Number of pages7
JournalArchives of Ophthalmology
Volume126
Issue number7
DOIs
StatePublished - Jul 2008

Fingerprint

Temazepam
Visual Acuity

ASJC Scopus subject areas

  • Ophthalmology

Cite this

Visual insignificance of the foveal pit : Reassessment of foveal hypoplasia as fovea plana. / Marmor, Michael F.; Choi, Stacey S.; Zawadzki, Robert; Werner, John S.

In: Archives of Ophthalmology, Vol. 126, No. 7, 07.2008, p. 907-913.

Research output: Contribution to journalArticle

@article{80fdf51eb951489181ebdbdfb94434cd,
title = "Visual insignificance of the foveal pit: Reassessment of foveal hypoplasia as fovea plana",
abstract = "Objectives: To elucidate the visual significance of the foveal pit by measuring foveal architecture and function and to reassess use of the term foveal hypoplasia (as visual acuity can vary among patients who lack a pit). Methods: We describe 4 patients who lack a foveal pit. Visual acuities ranged from 20/20 to 20/50. Stratus and Cirrus (Carl Zeiss Meditec, Dublin, California) optical coherence tomographs (OCXs) and multifocal electroretinograms were obtained. High-resolution retinal imaging on 2 of the participants was obtained by using a high-resolution Fourier-domain OCT and an adaptive optics flood-illuminated fundus camera. Results: No participants had a visible foveal pit with conventional OCT. Central widening of the outer nuclear layer and lengthening of cone outer segments were seen with high-resolution Fourier-domain OCT. Adaptive optics imaging showed normal cone diameters in the central 1° to 2°. Central multifocal electroretinogram responses were normal. Conclusions: We show that a foveal pit is not required for foveal cone specialization, anatomically or functionally. This helps to explain the potential for good acuity in the absence of a pit and raises questions about the visual role of the foveal pit. Because the term foveal hypoplasia commonly carries a negative functional implication, it may be more proper to call the anatomic lack of a pit fovea plana.",
author = "Marmor, {Michael F.} and Choi, {Stacey S.} and Robert Zawadzki and Werner, {John S}",
year = "2008",
month = "7",
doi = "10.1001/archopht.126.7.907",
language = "English (US)",
volume = "126",
pages = "907--913",
journal = "JAMA Ophthalmology",
issn = "2168-6165",
publisher = "American Medical Association",
number = "7",

}

TY - JOUR

T1 - Visual insignificance of the foveal pit

T2 - Reassessment of foveal hypoplasia as fovea plana

AU - Marmor, Michael F.

AU - Choi, Stacey S.

AU - Zawadzki, Robert

AU - Werner, John S

PY - 2008/7

Y1 - 2008/7

N2 - Objectives: To elucidate the visual significance of the foveal pit by measuring foveal architecture and function and to reassess use of the term foveal hypoplasia (as visual acuity can vary among patients who lack a pit). Methods: We describe 4 patients who lack a foveal pit. Visual acuities ranged from 20/20 to 20/50. Stratus and Cirrus (Carl Zeiss Meditec, Dublin, California) optical coherence tomographs (OCXs) and multifocal electroretinograms were obtained. High-resolution retinal imaging on 2 of the participants was obtained by using a high-resolution Fourier-domain OCT and an adaptive optics flood-illuminated fundus camera. Results: No participants had a visible foveal pit with conventional OCT. Central widening of the outer nuclear layer and lengthening of cone outer segments were seen with high-resolution Fourier-domain OCT. Adaptive optics imaging showed normal cone diameters in the central 1° to 2°. Central multifocal electroretinogram responses were normal. Conclusions: We show that a foveal pit is not required for foveal cone specialization, anatomically or functionally. This helps to explain the potential for good acuity in the absence of a pit and raises questions about the visual role of the foveal pit. Because the term foveal hypoplasia commonly carries a negative functional implication, it may be more proper to call the anatomic lack of a pit fovea plana.

AB - Objectives: To elucidate the visual significance of the foveal pit by measuring foveal architecture and function and to reassess use of the term foveal hypoplasia (as visual acuity can vary among patients who lack a pit). Methods: We describe 4 patients who lack a foveal pit. Visual acuities ranged from 20/20 to 20/50. Stratus and Cirrus (Carl Zeiss Meditec, Dublin, California) optical coherence tomographs (OCXs) and multifocal electroretinograms were obtained. High-resolution retinal imaging on 2 of the participants was obtained by using a high-resolution Fourier-domain OCT and an adaptive optics flood-illuminated fundus camera. Results: No participants had a visible foveal pit with conventional OCT. Central widening of the outer nuclear layer and lengthening of cone outer segments were seen with high-resolution Fourier-domain OCT. Adaptive optics imaging showed normal cone diameters in the central 1° to 2°. Central multifocal electroretinogram responses were normal. Conclusions: We show that a foveal pit is not required for foveal cone specialization, anatomically or functionally. This helps to explain the potential for good acuity in the absence of a pit and raises questions about the visual role of the foveal pit. Because the term foveal hypoplasia commonly carries a negative functional implication, it may be more proper to call the anatomic lack of a pit fovea plana.

UR - http://www.scopus.com/inward/record.url?scp=47549089269&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=47549089269&partnerID=8YFLogxK

U2 - 10.1001/archopht.126.7.907

DO - 10.1001/archopht.126.7.907

M3 - Article

C2 - 18625935

AN - SCOPUS:47549089269

VL - 126

SP - 907

EP - 913

JO - JAMA Ophthalmology

JF - JAMA Ophthalmology

SN - 2168-6165

IS - 7

ER -