Virulence of Brucella abortus isolated from cattle and water buffalo

Abiodun A. Adesiyun, Geoffrey T. Fosgate, Ravi Seebaransingh, Gabriel Brown, Simone Stoute, Alva Stewart-Johnson

Research output: Contribution to journalArticle

5 Scopus citations

Abstract

Brucellosis has been documented in domestic water buffalo (Bubalus bubalis) but published literature is limited despite the importance of this species in tropical agricultural systems. The objective of this study was to compare the virulence of Brucella abortus isolates recovered from cattle and water buffalo. Nineteen strains of B. abortus from cattle and domestic water buffalo in Trinidad were intraperitoneally inoculated into BALB/c mice. Spleens were cultured for B. abortus and histopathological severity scores were calculated based on lymphoid depletion, lymphoid necrosis, splenitis, and macrophage accumulation. A general linear model approach was used to estimate the effect of isolate source (cattle versus water buffalo) on virulence. Isolates of water buffalo origin were significantly less virulent in the mouse model based on recovered B. abortus from splenic tissues, spleen/weight ratio, and lymphoid necrosis but not overall histopathological severity scores. Further investigation of isolates recovered from water buffalo might provide the key to the development of procedures for brucellosis control in tropical environments.

Original languageEnglish (US)
Pages (from-to)13-16
Number of pages4
JournalTropical Animal Health and Production
Volume43
Issue number1
DOIs
StatePublished - Jan 1 2011
Externally publishedYes

Keywords

  • Brucellosis
  • Cattle
  • Trinidad
  • Virulence
  • Water buffalo

ASJC Scopus subject areas

  • Food Animals
  • Animal Science and Zoology

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  • Cite this

    Adesiyun, A. A., Fosgate, G. T., Seebaransingh, R., Brown, G., Stoute, S., & Stewart-Johnson, A. (2011). Virulence of Brucella abortus isolated from cattle and water buffalo. Tropical Animal Health and Production, 43(1), 13-16. https://doi.org/10.1007/s11250-010-9679-y