Abstract
Infectious bronchitis was diagnosed in 3-to-4-week-old pullets from an outbreak in a commercial flock in California. The disease was characterized by head swelling, watery discharge from the eyes and nostrils, and urates in kidneys. Mortality ranged from 1.8% to 12.5% per week. The isolation of a coronavirus from a suspension of pooled kidneys from clinically ill chickens at the fifth passage in 10-day-old chicken embryos, gross and histologic renal lesions, and seroconversion by enzyme-linked immunosorbent assay in inoculated birds suggested that the virus isolated was a nephrotrophic strain of infectious bronchitis virus (IBV). The virus isolate was found to be a previously unrecognized serotype, based on virus neutralization tests performed in embryonated chicken eggs. Nephropathogenicity of the IBV isolate was confirmed by inoculation of the viral isolate into specific-pathogen-free chicks and demonstration of renal lesions. The isolation of nephrotropic strains of IBV has not been reported previously from poultry in California.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 415-421 |
| Number of pages | 7 |
| Journal | Avian Diseases |
| Volume | 35 |
| Issue number | 2 |
| State | Published - Apr 1991 |
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ASJC Scopus subject areas
- Cancer Research
- Immunology
- veterinary(all)
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Viral pathogenesis of a nephrotropic infectious bronchitis virus isolated from commercial pullets. / Kinde, Hailu; Daft, B. M.; Castro, A. E.; Bickford, A. A.; Gelb, J.; Reynolds, B.
In: Avian Diseases, Vol. 35, No. 2, 04.1991, p. 415-421.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Viral pathogenesis of a nephrotropic infectious bronchitis virus isolated from commercial pullets.
AU - Kinde, Hailu
AU - Daft, B. M.
AU - Castro, A. E.
AU - Bickford, A. A.
AU - Gelb, J.
AU - Reynolds, B.
PY - 1991/4
Y1 - 1991/4
N2 - Infectious bronchitis was diagnosed in 3-to-4-week-old pullets from an outbreak in a commercial flock in California. The disease was characterized by head swelling, watery discharge from the eyes and nostrils, and urates in kidneys. Mortality ranged from 1.8% to 12.5% per week. The isolation of a coronavirus from a suspension of pooled kidneys from clinically ill chickens at the fifth passage in 10-day-old chicken embryos, gross and histologic renal lesions, and seroconversion by enzyme-linked immunosorbent assay in inoculated birds suggested that the virus isolated was a nephrotrophic strain of infectious bronchitis virus (IBV). The virus isolate was found to be a previously unrecognized serotype, based on virus neutralization tests performed in embryonated chicken eggs. Nephropathogenicity of the IBV isolate was confirmed by inoculation of the viral isolate into specific-pathogen-free chicks and demonstration of renal lesions. The isolation of nephrotropic strains of IBV has not been reported previously from poultry in California.
AB - Infectious bronchitis was diagnosed in 3-to-4-week-old pullets from an outbreak in a commercial flock in California. The disease was characterized by head swelling, watery discharge from the eyes and nostrils, and urates in kidneys. Mortality ranged from 1.8% to 12.5% per week. The isolation of a coronavirus from a suspension of pooled kidneys from clinically ill chickens at the fifth passage in 10-day-old chicken embryos, gross and histologic renal lesions, and seroconversion by enzyme-linked immunosorbent assay in inoculated birds suggested that the virus isolated was a nephrotrophic strain of infectious bronchitis virus (IBV). The virus isolate was found to be a previously unrecognized serotype, based on virus neutralization tests performed in embryonated chicken eggs. Nephropathogenicity of the IBV isolate was confirmed by inoculation of the viral isolate into specific-pathogen-free chicks and demonstration of renal lesions. The isolation of nephrotropic strains of IBV has not been reported previously from poultry in California.
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M3 - Article
C2 - 1649594
AN - SCOPUS:0026147662
VL - 35
SP - 415
EP - 421
JO - Avian Diseases
JF - Avian Diseases
SN - 0005-2086
IS - 2
ER -