Videodensitometric quantitation of stenosis: In vitro and in vivo validation

J Anthony Seibert, Daniel P Link, H. H. Hines, H. A. Baltaxe

Research output: Contribution to journalArticlepeer-review

7 Scopus citations


Percentage of stenosis of a vascular lumen was quantitated using a digital subtraction angiography system with videodensitometric analysis. To validate the algorithm and methods, we used precisely drilled Lucite rods of three inner diameters and various reduced diameters to give known luminal reduction. Both in vitro and in vivo results of stenosis measurements resulted in an excellent correlation between actual and measured values (correlation coefficient > 0.9 for all trials). Consistent underestimation of stenosis of about 5% was attributed to the various image degradations inherent with the imaging procedure and equipment. Errors were greatest with mid range stenoses and less at the extremes of the lesion values. An insufficient signal-to-noise ratio was caused by low photon flux and/or low contrast material concentration and overlying vasculature filled with contrast material. Overall, the videodensitometric technique is accurate, easy to implement, objective, and relatively free of errors associated with the geometric/edge detection method.

Original languageEnglish (US)
Pages (from-to)807-811
Number of pages5
Issue number3
StatePublished - 1985

ASJC Scopus subject areas

  • Radiological and Ultrasound Technology


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