Vesicostomy revisited

The best treatment for the hostile bladder in myelodysplastic children?

Shelby N. Morrisroe, R. Corey O'Connor, Dana K. Nanigian, Eric A Kurzrock, Anthony R Stone

Research output: Contribution to journalArticle

28 Citations (Scopus)

Abstract

OBJECTIVE: To evaluate the effects of vesicostomy on the urinary tract of myelodysplastic children in whom conservative bladder management with clean intermittent catheterization (CIC) has failed to preserve upper and lower urinary tract function. PATIENTS AND METHODS: Sixteen children with myelodysplasia underwent vesicostomy. Indications included worsening hydronephrosis, vesico-ureteric reflux (VUR), recurrent urinary tract infections (UTIs), and increasing renal insufficiency despite CIC and/or difficulty with CIC. The mean (range) age at vesicostomy was 36.5 (9-82) months and the follow-up 7.4 (2-16) years. RESULTS: Hydronephrosis resolved or improved in 12 of 14 children, the incidence of UTI decreased to one or fewer per year in 10, VUR resolved or improved in nine, and renal function improved or stabilized in six of seven patients. One patient initially presented with renal insufficiency and subsequently required dialysis despite vesicostomy. Complications occurred in three of 15 children, and included stomal stenosis and bladder calculi. The vesicostomy was closed in six patients after a mean of 4.4 (1.5-9) years. Four of these patients required concomitant bladder augmentation. CONCLUSIONS: Vesicostomy in myelodysplastic children is effective in preventing and/or resolving the deleterious consequences of a 'hostile' bladder. The procedure is uncomplicated, well tolerated, reversible and should be considered in managing children in whom conservative management by CIC has failed.

Original languageEnglish (US)
Pages (from-to)397-400
Number of pages4
JournalBJU International
Volume96
Issue number3
DOIs
StatePublished - Aug 2005

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Cystostomy
Intermittent Urethral Catheterization
Urinary Bladder
Hydronephrosis
Urinary Tract
Urinary Tract Infections
Renal Insufficiency
Therapeutics
Urinary Bladder Calculi
Dialysis
Pathologic Constriction
Kidney
Incidence

Keywords

  • Myelodysplasia
  • Treatment outcome
  • Vesicostomy

ASJC Scopus subject areas

  • Urology

Cite this

Vesicostomy revisited : The best treatment for the hostile bladder in myelodysplastic children? / Morrisroe, Shelby N.; O'Connor, R. Corey; Nanigian, Dana K.; Kurzrock, Eric A; Stone, Anthony R.

In: BJU International, Vol. 96, No. 3, 08.2005, p. 397-400.

Research output: Contribution to journalArticle

Morrisroe, Shelby N. ; O'Connor, R. Corey ; Nanigian, Dana K. ; Kurzrock, Eric A ; Stone, Anthony R. / Vesicostomy revisited : The best treatment for the hostile bladder in myelodysplastic children?. In: BJU International. 2005 ; Vol. 96, No. 3. pp. 397-400.
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