Version 3 of the Alzheimer Disease Centers’ Neuropsychological Test Battery in the Uniform Data Set (UDS)

Sandra Weintraub, Lilah Besser, Hiroko H. Dodge, Merilee Teylan, Steven Ferris, Felicia C. Goldstein, Bruno Giordani, Joel Kramer, David Loewenstein, Dan Marson, Dan M Mungas, David Salmon, Kathleen Welsh-Bohmer, Xiao Hua Zhou, Steven D. Shirk, Alireza Atri, Walter A. Kukull, Creighton Phelps, John C. Morris

Research output: Contribution to journalArticle

36 Scopus citations

Abstract

Introduction: The neuropsychological battery of the Uniform Data Set (UDSNB) was implemented in 2005 by the National Institute on Aging (NIA) Alzheimer Disease Centers program to measure cognitive performance in dementia and mild cognitive impairment due to Alzheimer Disease. This paper describes a revision, the UDSNB 3.0. Methods: The Neuropsychology Work Group of the NIA Clinical Task Force recommended revisions through a process of due diligence to address shortcomings of the original battery. The UDSNB 3.0 covers episodic memory, processing speed, executive function, language, and constructional ability. Data from 3602 cognitively normal participants in the National Alzheimer Coordinating Center database were analyzed. Results: Descriptive statistics are presented. Multivariable linear regression analyses demonstrated score differences by age, sex, and education and were also used to create a normative calculator available online. Discussion: The UDSNB 3.0 neuropsychological battery provides a valuable non proprietary resource for conducting research on cognitive aging and dementia.

Original languageEnglish (US)
JournalAlzheimer Disease and Associated Disorders
DOIs
StateAccepted/In press - Dec 13 2017

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Keywords

  • cognition
  • dementia
  • neuropsychological test
  • UDS

ASJC Scopus subject areas

  • Clinical Psychology
  • Gerontology
  • Geriatrics and Gerontology
  • Psychiatry and Mental health

Cite this

Weintraub, S., Besser, L., Dodge, H. H., Teylan, M., Ferris, S., Goldstein, F. C., Giordani, B., Kramer, J., Loewenstein, D., Marson, D., Mungas, D. M., Salmon, D., Welsh-Bohmer, K., Zhou, X. H., Shirk, S. D., Atri, A., Kukull, W. A., Phelps, C., & Morris, J. C. (Accepted/In press). Version 3 of the Alzheimer Disease Centers’ Neuropsychological Test Battery in the Uniform Data Set (UDS). Alzheimer Disease and Associated Disorders. https://doi.org/10.1097/WAD.0000000000000223