Verapamil sensitive incessant ventricular tachycardia in the newborn

Anwer Dhala, David A. Lewis, Jeffrey Garland, Andrew N Pelech

Research output: Contribution to journalArticle

7 Citations (Scopus)

Abstract

Incessant VTs in infancy are often poorly tolerated. Response to conventional antiarrhythmic therapy is disappointing. The present case involves a 3-week-old infant with an incessant VT of a left bundle branch block, and normal axis morphology. This tachycardia was inducible with both atrial and ventricular pacing, but not by premature stimulation. Tachycardia persisted despite treatment with adenosine, esmolol, procainamide, and flecainide. Intravenous verapamil suppressed tachycardia and prevented inducibility, and no further recurrences were seen on oral verapamil. This case suggests that some incessant VTs in infancy may be due to calcium channel related afterdepolarizations or triggered activation.

Original languageEnglish (US)
Pages (from-to)1652-1654
Number of pages3
JournalPACE - Pacing and Clinical Electrophysiology
Volume19
Issue number11 I
StatePublished - 1996
Externally publishedYes

Fingerprint

Ventricular Tachycardia
Verapamil
Tachycardia
Newborn Infant
Flecainide
Procainamide
Bundle-Branch Block
Calcium Channels
Adenosine
Recurrence
Therapeutics

Keywords

  • neonate
  • ventricular tachycardias

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

Cite this

Verapamil sensitive incessant ventricular tachycardia in the newborn. / Dhala, Anwer; Lewis, David A.; Garland, Jeffrey; Pelech, Andrew N.

In: PACE - Pacing and Clinical Electrophysiology, Vol. 19, No. 11 I, 1996, p. 1652-1654.

Research output: Contribution to journalArticle

Dhala, Anwer ; Lewis, David A. ; Garland, Jeffrey ; Pelech, Andrew N. / Verapamil sensitive incessant ventricular tachycardia in the newborn. In: PACE - Pacing and Clinical Electrophysiology. 1996 ; Vol. 19, No. 11 I. pp. 1652-1654.
@article{e797f884276b427f9191a8dd03cf4674,
title = "Verapamil sensitive incessant ventricular tachycardia in the newborn",
abstract = "Incessant VTs in infancy are often poorly tolerated. Response to conventional antiarrhythmic therapy is disappointing. The present case involves a 3-week-old infant with an incessant VT of a left bundle branch block, and normal axis morphology. This tachycardia was inducible with both atrial and ventricular pacing, but not by premature stimulation. Tachycardia persisted despite treatment with adenosine, esmolol, procainamide, and flecainide. Intravenous verapamil suppressed tachycardia and prevented inducibility, and no further recurrences were seen on oral verapamil. This case suggests that some incessant VTs in infancy may be due to calcium channel related afterdepolarizations or triggered activation.",
keywords = "neonate, ventricular tachycardias",
author = "Anwer Dhala and Lewis, {David A.} and Jeffrey Garland and Pelech, {Andrew N}",
year = "1996",
language = "English (US)",
volume = "19",
pages = "1652--1654",
journal = "PACE - Pacing and Clinical Electrophysiology",
issn = "0147-8389",
publisher = "Wiley-Blackwell",
number = "11 I",

}

TY - JOUR

T1 - Verapamil sensitive incessant ventricular tachycardia in the newborn

AU - Dhala, Anwer

AU - Lewis, David A.

AU - Garland, Jeffrey

AU - Pelech, Andrew N

PY - 1996

Y1 - 1996

N2 - Incessant VTs in infancy are often poorly tolerated. Response to conventional antiarrhythmic therapy is disappointing. The present case involves a 3-week-old infant with an incessant VT of a left bundle branch block, and normal axis morphology. This tachycardia was inducible with both atrial and ventricular pacing, but not by premature stimulation. Tachycardia persisted despite treatment with adenosine, esmolol, procainamide, and flecainide. Intravenous verapamil suppressed tachycardia and prevented inducibility, and no further recurrences were seen on oral verapamil. This case suggests that some incessant VTs in infancy may be due to calcium channel related afterdepolarizations or triggered activation.

AB - Incessant VTs in infancy are often poorly tolerated. Response to conventional antiarrhythmic therapy is disappointing. The present case involves a 3-week-old infant with an incessant VT of a left bundle branch block, and normal axis morphology. This tachycardia was inducible with both atrial and ventricular pacing, but not by premature stimulation. Tachycardia persisted despite treatment with adenosine, esmolol, procainamide, and flecainide. Intravenous verapamil suppressed tachycardia and prevented inducibility, and no further recurrences were seen on oral verapamil. This case suggests that some incessant VTs in infancy may be due to calcium channel related afterdepolarizations or triggered activation.

KW - neonate

KW - ventricular tachycardias

UR - http://www.scopus.com/inward/record.url?scp=0029976852&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0029976852&partnerID=8YFLogxK

M3 - Article

C2 - 8946465

AN - SCOPUS:0029976852

VL - 19

SP - 1652

EP - 1654

JO - PACE - Pacing and Clinical Electrophysiology

JF - PACE - Pacing and Clinical Electrophysiology

SN - 0147-8389

IS - 11 I

ER -