Abstract
Arginine vasopressin (AVP or vasopressin) is a neurophypophyseal peptide hormone with both vasopressor and antidiuretic properties. This review will briefly discuss the chemistry and physiology of AVP, with the main focus being on AVP and the hemostatic system. Recent data on the effects of AVP, and its analogues, on platelet function will be highlighted. AVP-induced platelet activation could explain, in part, the benefit seen with AVP infusions in gastrointestinal bleeding. These data also suggest that AVP may have a role in physiologic hemostasis and platelet activation.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 15-21 |
| Number of pages | 7 |
| Journal | Platelets |
| Volume | 8 |
| Issue number | 1 |
| State | Published - 1997 |
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ASJC Scopus subject areas
- Cell Biology
- Hematology
Cite this
Vasopressin and platelets : A concise review. / Wun, Theodore.
In: Platelets, Vol. 8, No. 1, 1997, p. 15-21.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Vasopressin and platelets
T2 - A concise review
AU - Wun, Theodore
PY - 1997
Y1 - 1997
N2 - Arginine vasopressin (AVP or vasopressin) is a neurophypophyseal peptide hormone with both vasopressor and antidiuretic properties. This review will briefly discuss the chemistry and physiology of AVP, with the main focus being on AVP and the hemostatic system. Recent data on the effects of AVP, and its analogues, on platelet function will be highlighted. AVP-induced platelet activation could explain, in part, the benefit seen with AVP infusions in gastrointestinal bleeding. These data also suggest that AVP may have a role in physiologic hemostasis and platelet activation.
AB - Arginine vasopressin (AVP or vasopressin) is a neurophypophyseal peptide hormone with both vasopressor and antidiuretic properties. This review will briefly discuss the chemistry and physiology of AVP, with the main focus being on AVP and the hemostatic system. Recent data on the effects of AVP, and its analogues, on platelet function will be highlighted. AVP-induced platelet activation could explain, in part, the benefit seen with AVP infusions in gastrointestinal bleeding. These data also suggest that AVP may have a role in physiologic hemostasis and platelet activation.
UR - http://www.scopus.com/inward/record.url?scp=0030970208&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0030970208&partnerID=8YFLogxK
M3 - Article
C2 - 16793628
AN - SCOPUS:0030970208
VL - 8
SP - 15
EP - 21
JO - Platelets
JF - Platelets
SN - 0953-7104
IS - 1
ER -