Vascular factors in dementia: An overview

Research output: Contribution to journalArticlepeer-review

74 Scopus citations


Alzheimer's disease and cerebrovascular disease are two illnesses common to the elderly. Conventional wisdom has sought to separately describe and treat these two diseases. Accumulating evidence, however, shows that cerebrovascular risk factors may cause asymptomatic brain injury, share genetic risk with Alzheimer's disease and possibly accelerate the Alzheimer's process. Such evidence suggests that these two diseases may act additively or synergistically to cause clinical dementia. This review focuses on evolving data that support this hypothesis.

Original languageEnglish (US)
Pages (from-to)19-23
Number of pages5
JournalJournal of the Neurological Sciences
Issue number1-2 SPEC.ISS.
StatePublished - Nov 15 2004


  • Alzheimer disease
  • Cerebrovascular disease
  • Dementia

ASJC Scopus subject areas

  • Aging
  • Clinical Neurology
  • Surgery
  • Developmental Neuroscience
  • Neurology
  • Neuroscience(all)


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