Vascular artifact mimicking thrombosis on mr imaging using ferumoxytol as a contrast agent in abdominal vascular assessment

Ghaneh Fananapazir, Daniele Marin, Paul V. Suhocki, Charles Y. Kim, Mustafa R. Bashir

Research output: Contribution to journalArticle

16 Scopus citations

Abstract

Purpose To describe an artifact that mimics thrombosis when assessing abdominal vasculature on magnetic resonance (MR) imaging using ferumoxytol in patients with contraindications to gadolinium-based contrast agents and to evaluate factors that may contribute to this artifact. Materials and Methods Three radiologists in consensus retrospectively evaluated 61 abdominal MR imaging examinations using ferumoxytol as an intravenous contrast agent for the presence of an observed artifact that can mimic thrombosis. Patient demographics and contrast agent bolus concentrations were compared with an unpaired Wilcoxon signed rank test. Results An artifact mimicking thrombosis was observed in 30 of 61 examinations, all on the arterial phase sequences. In examinations with this artifact, the average concentration of administered ferumoxytol was greater than in examinations where the artifact was not observed (P <.01). Several additional vascular findings were observed, including portal vein thrombosis (n = 2) and aneurysm (n = 1), renal vein thrombosis (n = 2), abdominal aortic aneurysm (n = 1), abdominal and iliac artery dissection (n = 3), and sequelae of portal hypertension (n = 8). Conclusions Although MR imaging using ferumoxytol as an intravenous contrast agent can be useful in detecting abdominal vascular abnormalities, an artifact mimicking vascular thrombosis was observed in nearly half of the examinations.

Original languageEnglish (US)
Pages (from-to)969-976
Number of pages8
JournalJournal of Vascular and Interventional Radiology
Volume25
Issue number6
DOIs
StatePublished - 2014

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging
  • Cardiology and Cardiovascular Medicine

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