Variation in assessing sella turcica tomograms for pituitary microadenomas

L. Gordis, Ellen B Gold, L. Libauer

Research output: Contribution to journalArticle

6 Citations (Scopus)

Abstract

A multicenter study evaluated the extent of observer variation in interpretation of hypocycloidal polytomograms of the sella turcica in women with amenorrhea and/or galactorrhea, some of whom had surgically verified pituitary adenomas. Three physicians - 2 neuroradiologists and 1 neurosurgeon - independently and without additional clinical information about the patients reviewed 45 sets of tomograms, 16 of which had originally been classified as abnormal, 23 as normal, and 6 as equivocal. Two or more of these physicians agreed with the original reading in 58% of all cases: in 81% of those originally read as abnormal, 56% of those originally read as normal, but in none of those originally read as equivocal. In 8 women with surgically confirmed pituitary abnormalities, readers' accuracy ranged from 50 to 88%. The physicians varied considerably in the proportion of tomograms read as normal (16 to 45%) or abnormal (38 to 71%), but overall, for only 11% of the tomograms was there no agreement among any of the 3 reviewers. The findings indicate that even among highly experienced physicians, there is considerable variation in the interpretation of polytomograms of the sella for women with amenorrhea and/or galactorrhea.

Original languageEnglish (US)
Pages (from-to)700-704
Number of pages5
JournalObstetrics and Gynecology
Volume60
Issue number6
StatePublished - 1982
Externally publishedYes

Fingerprint

Sella Turcica
Galactorrhea
Physicians
Amenorrhea
Observer Variation
Pituitary Neoplasms
Multicenter Studies
Reading

ASJC Scopus subject areas

  • Obstetrics and Gynecology

Cite this

Variation in assessing sella turcica tomograms for pituitary microadenomas. / Gordis, L.; Gold, Ellen B; Libauer, L.

In: Obstetrics and Gynecology, Vol. 60, No. 6, 1982, p. 700-704.

Research output: Contribution to journalArticle

@article{2cebcada445541f2b452ebe04b0aa320,
title = "Variation in assessing sella turcica tomograms for pituitary microadenomas",
abstract = "A multicenter study evaluated the extent of observer variation in interpretation of hypocycloidal polytomograms of the sella turcica in women with amenorrhea and/or galactorrhea, some of whom had surgically verified pituitary adenomas. Three physicians - 2 neuroradiologists and 1 neurosurgeon - independently and without additional clinical information about the patients reviewed 45 sets of tomograms, 16 of which had originally been classified as abnormal, 23 as normal, and 6 as equivocal. Two or more of these physicians agreed with the original reading in 58{\%} of all cases: in 81{\%} of those originally read as abnormal, 56{\%} of those originally read as normal, but in none of those originally read as equivocal. In 8 women with surgically confirmed pituitary abnormalities, readers' accuracy ranged from 50 to 88{\%}. The physicians varied considerably in the proportion of tomograms read as normal (16 to 45{\%}) or abnormal (38 to 71{\%}), but overall, for only 11{\%} of the tomograms was there no agreement among any of the 3 reviewers. The findings indicate that even among highly experienced physicians, there is considerable variation in the interpretation of polytomograms of the sella for women with amenorrhea and/or galactorrhea.",
author = "L. Gordis and Gold, {Ellen B} and L. Libauer",
year = "1982",
language = "English (US)",
volume = "60",
pages = "700--704",
journal = "Obstetrics and Gynecology",
issn = "0029-7844",
publisher = "Lippincott Williams and Wilkins",
number = "6",

}

TY - JOUR

T1 - Variation in assessing sella turcica tomograms for pituitary microadenomas

AU - Gordis, L.

AU - Gold, Ellen B

AU - Libauer, L.

PY - 1982

Y1 - 1982

N2 - A multicenter study evaluated the extent of observer variation in interpretation of hypocycloidal polytomograms of the sella turcica in women with amenorrhea and/or galactorrhea, some of whom had surgically verified pituitary adenomas. Three physicians - 2 neuroradiologists and 1 neurosurgeon - independently and without additional clinical information about the patients reviewed 45 sets of tomograms, 16 of which had originally been classified as abnormal, 23 as normal, and 6 as equivocal. Two or more of these physicians agreed with the original reading in 58% of all cases: in 81% of those originally read as abnormal, 56% of those originally read as normal, but in none of those originally read as equivocal. In 8 women with surgically confirmed pituitary abnormalities, readers' accuracy ranged from 50 to 88%. The physicians varied considerably in the proportion of tomograms read as normal (16 to 45%) or abnormal (38 to 71%), but overall, for only 11% of the tomograms was there no agreement among any of the 3 reviewers. The findings indicate that even among highly experienced physicians, there is considerable variation in the interpretation of polytomograms of the sella for women with amenorrhea and/or galactorrhea.

AB - A multicenter study evaluated the extent of observer variation in interpretation of hypocycloidal polytomograms of the sella turcica in women with amenorrhea and/or galactorrhea, some of whom had surgically verified pituitary adenomas. Three physicians - 2 neuroradiologists and 1 neurosurgeon - independently and without additional clinical information about the patients reviewed 45 sets of tomograms, 16 of which had originally been classified as abnormal, 23 as normal, and 6 as equivocal. Two or more of these physicians agreed with the original reading in 58% of all cases: in 81% of those originally read as abnormal, 56% of those originally read as normal, but in none of those originally read as equivocal. In 8 women with surgically confirmed pituitary abnormalities, readers' accuracy ranged from 50 to 88%. The physicians varied considerably in the proportion of tomograms read as normal (16 to 45%) or abnormal (38 to 71%), but overall, for only 11% of the tomograms was there no agreement among any of the 3 reviewers. The findings indicate that even among highly experienced physicians, there is considerable variation in the interpretation of polytomograms of the sella for women with amenorrhea and/or galactorrhea.

UR - http://www.scopus.com/inward/record.url?scp=0020421435&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0020421435&partnerID=8YFLogxK

M3 - Article

C2 - 6890658

AN - SCOPUS:0020421435

VL - 60

SP - 700

EP - 704

JO - Obstetrics and Gynecology

JF - Obstetrics and Gynecology

SN - 0029-7844

IS - 6

ER -