Value of axial and coronal maximum intensity projection (MIP) images in the detection of pulmonary nodules by multislice spiral CT: Comparison with axial 1-mm and 5-mm slices

Ray Valencia, Timm Denecke, Lukas Lehmkuhl, Frank Fischbach, Roland Felix, Friedrich D Knollmann

Research output: Contribution to journalArticle

62 Scopus citations

Abstract

The purpose of this study was to investigate the diagnostic accuracy of non-overlapping 10-mm axial and coronal maximum intensity projections (MIP) in comparison with standard axial 1-mm and 5-mm slices in the detection of pulmonary nodules. Sixty patients with suspected nodules who underwent multislice spiral CT of the chest were evaluated. Axial 1-mm and 5-mm slices as well as non-overlapping 10-mm axial/coronal MIPs were interpreted independently by three blinded radiologists. After initial review, a retrospective consensus session was performed for agreement on final nodule counts using the axial 1-mm slices as gold standard. Small nodules of less than 5 mm in size were most accurately detected by the axial MIPs. Receiver operating characteristic (ROC) analysis of these small nodules showed that 5-mm slices were not capable of a statistically significant differentiation of nodules from other focal lesions in two observers (p=0.034 and p=0.012, respectively) whereas 1-mm slices and coronal/axial MIPs did allow a statistically significant differentiation in all observers (p <0.001). Nodules larger than 5 mm were equally well depicted with all modalities. Non-overlapping 10-mm axial MIPs improve the accuracy in the detection of small pulmonary nodules.

Original languageEnglish (US)
Pages (from-to)325-332
Number of pages8
JournalEuropean Radiology
Volume16
Issue number2
DOIs
StatePublished - Feb 2006
Externally publishedYes

Keywords

  • Maximum intensity projection
  • MIP
  • Multislice computed tomography
  • Pulmonarynodule
  • Thoracic CT

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging
  • Radiological and Ultrasound Technology

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