Validation of the Japanese version of the Fisk Fatigue Severity Score (FFSS) in Japanese patients with primary biliary cirrhosis

Atsushi Tanaka; Hiroki Takahashi; Saeko Nezu; Yoshiyuki Ueno; Kentaro Kikuchi; Akitaka Shibuya; Hiromasa Ohira; Mikio Zeniya; Lorenzo Montali; Pietro Invernizzi; Hajime Takikawa

doi:10.2957/kanzo.50.51

Validation of the Japanese version of the Fisk Fatigue Severity Score (FFSS) in Japanese patients with primary biliary cirrhosis

Atsushi Tanaka, Hiroki Takahashi, Saeko Nezu, Yoshiyuki Ueno, Kentaro Kikuchi, Akitaka Shibuya, Hiromasa Ohira, Mikio Zeniya, Lorenzo Montali, Pietro Invernizzi, Hajime Takikawa

Research output: Contribution to journal › Article

Abstract

Fatigue is considered to be a specific symptom of primary biliary cirrhosis (PBC), while the prevalence of fatigue in Japanese PBC patients remain unclear, probably due to lack of objective scales for assessment of fatigue in Japanese. In this study, we developed the Japanese version of Fisk Fatigue Severity Score (FFSS), frequently employed in the previous studies, and examined the validity and reliablity in 166 Japanese PBC patients. Cronbach's alfa coefficients in each subscale of the FFSS ranged from 0.94 to 0.96. The correlations between each subscale of FFSS and SF-36 were well acceptable. In particular, the 'vitality' and 'role physical' subscales of SF-36 were well correlated with subscales of FFSS. The factor analysis of the FFSS yielded 4 factors which explain 66% of the total variance. This study validated the Japanese version of FFSS, which provide a powerful tool for the evaluation of fatigue of Japanese PBC patients.

Original language	English (US)
Pages (from-to)	51-59
Number of pages	9
Journal	Acta Hepatologica Japonica
Volume	50
Issue number	2
DOIs	https://doi.org/10.2957/kanzo.50.51
State	Published - 2009
Externally published	Yes

Keywords

Autoimmune liver disease
Fatigue
Objective assessment scale
Primary biliary cirrhosis
Quality of life

ASJC Scopus subject areas

Hepatology

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Tanaka, A., Takahashi, H., Nezu, S., Ueno, Y., Kikuchi, K., Shibuya, A., Ohira, H., Zeniya, M., Montali, L., Invernizzi, P., & Takikawa, H. (2009). Validation of the Japanese version of the Fisk Fatigue Severity Score (FFSS) in Japanese patients with primary biliary cirrhosis. Acta Hepatologica Japonica, 50(2), 51-59. https://doi.org/10.2957/kanzo.50.51

Validation of the Japanese version of the Fisk Fatigue Severity Score (FFSS) in Japanese patients with primary biliary cirrhosis. / Tanaka, Atsushi; Takahashi, Hiroki; Nezu, Saeko; Ueno, Yoshiyuki; Kikuchi, Kentaro; Shibuya, Akitaka; Ohira, Hiromasa; Zeniya, Mikio; Montali, Lorenzo; Invernizzi, Pietro; Takikawa, Hajime.

In: Acta Hepatologica Japonica, Vol. 50, No. 2, 2009, p. 51-59.

Research output: Contribution to journal › Article

Tanaka, Atsushi ; Takahashi, Hiroki ; Nezu, Saeko ; Ueno, Yoshiyuki ; Kikuchi, Kentaro ; Shibuya, Akitaka ; Ohira, Hiromasa ; Zeniya, Mikio ; Montali, Lorenzo ; Invernizzi, Pietro ; Takikawa, Hajime. / Validation of the Japanese version of the Fisk Fatigue Severity Score (FFSS) in Japanese patients with primary biliary cirrhosis. In: Acta Hepatologica Japonica. 2009 ; Vol. 50, No. 2. pp. 51-59.

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abstract = "Fatigue is considered to be a specific symptom of primary biliary cirrhosis (PBC), while the prevalence of fatigue in Japanese PBC patients remain unclear, probably due to lack of objective scales for assessment of fatigue in Japanese. In this study, we developed the Japanese version of Fisk Fatigue Severity Score (FFSS), frequently employed in the previous studies, and examined the validity and reliablity in 166 Japanese PBC patients. Cronbach's alfa coefficients in each subscale of the FFSS ranged from 0.94 to 0.96. The correlations between each subscale of FFSS and SF-36 were well acceptable. In particular, the 'vitality' and 'role physical' subscales of SF-36 were well correlated with subscales of FFSS. The factor analysis of the FFSS yielded 4 factors which explain 66% of the total variance. This study validated the Japanese version of FFSS, which provide a powerful tool for the evaluation of fatigue of Japanese PBC patients.",

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AU - Kikuchi, Kentaro

AU - Shibuya, Akitaka

AU - Ohira, Hiromasa

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AU - Montali, Lorenzo

AU - Invernizzi, Pietro

AU - Takikawa, Hajime

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AB - Fatigue is considered to be a specific symptom of primary biliary cirrhosis (PBC), while the prevalence of fatigue in Japanese PBC patients remain unclear, probably due to lack of objective scales for assessment of fatigue in Japanese. In this study, we developed the Japanese version of Fisk Fatigue Severity Score (FFSS), frequently employed in the previous studies, and examined the validity and reliablity in 166 Japanese PBC patients. Cronbach's alfa coefficients in each subscale of the FFSS ranged from 0.94 to 0.96. The correlations between each subscale of FFSS and SF-36 were well acceptable. In particular, the 'vitality' and 'role physical' subscales of SF-36 were well correlated with subscales of FFSS. The factor analysis of the FFSS yielded 4 factors which explain 66% of the total variance. This study validated the Japanese version of FFSS, which provide a powerful tool for the evaluation of fatigue of Japanese PBC patients.

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