Abstract
Immunological priming, protection and memory are the usual consequences of infection. However, in some instances, the host response might be inadequate or inappropriate, possibly as a result of strategies employed by the pathogen. Here, Stephen McSorley and Paul Garside discuss how oral tolerance protocols that have been employed recently in autoimmune disease models could be adapted specifically to prevent the development of inappropriate or pathological responses that occur during infection, thus functioning as effective vaccines.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 555-560 |
| Number of pages | 6 |
| Journal | Immunology Today |
| Volume | 20 |
| Issue number | 12 |
| DOIs | |
| State | Published - Dec 1 1999 |
| Externally published | Yes |
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ASJC Scopus subject areas
- Immunology
Cite this
Vaccination by inducing oral tolerance? / Mcsorley, Stephen J; Garside, Paul.
In: Immunology Today, Vol. 20, No. 12, 01.12.1999, p. 555-560.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Vaccination by inducing oral tolerance?
AU - Mcsorley, Stephen J
AU - Garside, Paul
PY - 1999/12/1
Y1 - 1999/12/1
N2 - Immunological priming, protection and memory are the usual consequences of infection. However, in some instances, the host response might be inadequate or inappropriate, possibly as a result of strategies employed by the pathogen. Here, Stephen McSorley and Paul Garside discuss how oral tolerance protocols that have been employed recently in autoimmune disease models could be adapted specifically to prevent the development of inappropriate or pathological responses that occur during infection, thus functioning as effective vaccines.
AB - Immunological priming, protection and memory are the usual consequences of infection. However, in some instances, the host response might be inadequate or inappropriate, possibly as a result of strategies employed by the pathogen. Here, Stephen McSorley and Paul Garside discuss how oral tolerance protocols that have been employed recently in autoimmune disease models could be adapted specifically to prevent the development of inappropriate or pathological responses that occur during infection, thus functioning as effective vaccines.
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UR - http://www.scopus.com/inward/citedby.url?scp=0033485471&partnerID=8YFLogxK
U2 - 10.1016/S0167-5699(99)01539-X
DO - 10.1016/S0167-5699(99)01539-X
M3 - Article
C2 - 10562706
AN - SCOPUS:0033485471
VL - 20
SP - 555
EP - 560
JO - Trends in Immunology
JF - Trends in Immunology
SN - 1471-4906
IS - 12
ER -