Abstract
Background: The need for routine neuroimaging after extracorporeal membrane oxygenation (ECMO) and the optimal radiographic study remains unclear. We sought to evaluate the correlation between findings on head ultrasound (HUS) and magnetic resonance imaging (MRI) and determine the association of these findings to neurodevelopmental outcome. Methods: A retrospective review was performed (2003-2010) to identify neonates who had a MRI after ECMO. Each MRI was reviewed by a single pediatric neuroradiologist. Neurodevelopmental data was collected from the high-risk neonatal follow-up clinic. Results: Fifty neonates had a MRI (venoarterial 37, venovenous 13) after ECMO. HUS was abnormal in 24%, whereas MRI was abnormal in 62%. All infants with an abnormal HUS had an abnormal MRI, but an additional 50% of patients with a normal HUS had an abnormal MRI. Venoarterial ECMO was significantly associated with an abnormal MRI. Follow-up data was available for 26 neonates. The only predictor of abnormal neurodevelopment was the need for supplemental tube feeds at discharge. Conclusions: MRI identified significantly more abnormalities compared to routine HUS after neonatal ECMO. However, neither MRI nor HUS findings correlated with early neurodevelopmental outcome. Feeding ability at discharge was the overall best predictor of neurologic impairment in survivors.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 76-80 |
| Number of pages | 5 |
| Journal | Journal of Pediatric Surgery |
| Volume | 47 |
| Issue number | 1 |
| DOIs | |
| State | Published - Jan 1 2012 |
| Externally published | Yes |
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Keywords
- Extracorporeal membrane oxygenation
- Magnetic resonance imaging
- Neonates
- Neurodevelopmental outcome
- Ultrasound
ASJC Scopus subject areas
- Surgery
- Pediatrics, Perinatology, and Child Health
Cite this
Utility of neuroradiographic imaging in predicting outcomes after neonatal extracorporeal membrane oxygenation. / Rollins, Michael D.; Yoder, Bradley A.; Moore, Kevin R.; Barnhart, Douglas C.; Jones, Chris; Null, Donald; Digeronimo, Robert J.
In: Journal of Pediatric Surgery, Vol. 47, No. 1, 01.01.2012, p. 76-80.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Utility of neuroradiographic imaging in predicting outcomes after neonatal extracorporeal membrane oxygenation
AU - Rollins, Michael D.
AU - Yoder, Bradley A.
AU - Moore, Kevin R.
AU - Barnhart, Douglas C.
AU - Jones, Chris
AU - Null, Donald
AU - Digeronimo, Robert J.
PY - 2012/1/1
Y1 - 2012/1/1
N2 - Background: The need for routine neuroimaging after extracorporeal membrane oxygenation (ECMO) and the optimal radiographic study remains unclear. We sought to evaluate the correlation between findings on head ultrasound (HUS) and magnetic resonance imaging (MRI) and determine the association of these findings to neurodevelopmental outcome. Methods: A retrospective review was performed (2003-2010) to identify neonates who had a MRI after ECMO. Each MRI was reviewed by a single pediatric neuroradiologist. Neurodevelopmental data was collected from the high-risk neonatal follow-up clinic. Results: Fifty neonates had a MRI (venoarterial 37, venovenous 13) after ECMO. HUS was abnormal in 24%, whereas MRI was abnormal in 62%. All infants with an abnormal HUS had an abnormal MRI, but an additional 50% of patients with a normal HUS had an abnormal MRI. Venoarterial ECMO was significantly associated with an abnormal MRI. Follow-up data was available for 26 neonates. The only predictor of abnormal neurodevelopment was the need for supplemental tube feeds at discharge. Conclusions: MRI identified significantly more abnormalities compared to routine HUS after neonatal ECMO. However, neither MRI nor HUS findings correlated with early neurodevelopmental outcome. Feeding ability at discharge was the overall best predictor of neurologic impairment in survivors.
AB - Background: The need for routine neuroimaging after extracorporeal membrane oxygenation (ECMO) and the optimal radiographic study remains unclear. We sought to evaluate the correlation between findings on head ultrasound (HUS) and magnetic resonance imaging (MRI) and determine the association of these findings to neurodevelopmental outcome. Methods: A retrospective review was performed (2003-2010) to identify neonates who had a MRI after ECMO. Each MRI was reviewed by a single pediatric neuroradiologist. Neurodevelopmental data was collected from the high-risk neonatal follow-up clinic. Results: Fifty neonates had a MRI (venoarterial 37, venovenous 13) after ECMO. HUS was abnormal in 24%, whereas MRI was abnormal in 62%. All infants with an abnormal HUS had an abnormal MRI, but an additional 50% of patients with a normal HUS had an abnormal MRI. Venoarterial ECMO was significantly associated with an abnormal MRI. Follow-up data was available for 26 neonates. The only predictor of abnormal neurodevelopment was the need for supplemental tube feeds at discharge. Conclusions: MRI identified significantly more abnormalities compared to routine HUS after neonatal ECMO. However, neither MRI nor HUS findings correlated with early neurodevelopmental outcome. Feeding ability at discharge was the overall best predictor of neurologic impairment in survivors.
KW - Extracorporeal membrane oxygenation
KW - Magnetic resonance imaging
KW - Neonates
KW - Neurodevelopmental outcome
KW - Ultrasound
UR - http://www.scopus.com/inward/record.url?scp=84855824422&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84855824422&partnerID=8YFLogxK
U2 - 10.1016/j.jpedsurg.2011.10.016
DO - 10.1016/j.jpedsurg.2011.10.016
M3 - Article
C2 - 22244396
AN - SCOPUS:84855824422
VL - 47
SP - 76
EP - 80
JO - Journal of Pediatric Surgery
JF - Journal of Pediatric Surgery
SN - 0022-3468
IS - 1
ER -