Utf1: Goldilocks for ESC bivalency

Agnieszka I. Laskowski, Paul S Knoepfler

Research output: Contribution to journalArticle

5 Citations (Scopus)

Abstract

Recently in Cell, Jia et al. (2012) reported novel Utf1-controlled mechanisms of maintaining pluripotency and self-renewal in embryonic stem cells (ESCs). Utf1 buffers bivalent gene expression by competitive binding with polycomb repressive complex 2 and initiation of mRNA degradation.

Original languageEnglish (US)
Pages (from-to)732-734
Number of pages3
JournalCell Stem Cell
Volume11
Issue number6
DOIs
StatePublished - Dec 7 2012

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Polycomb Repressive Complex 2
Competitive Binding
RNA Stability
Embryonic Stem Cells
Buffers
Gene Expression

ASJC Scopus subject areas

  • Cell Biology
  • Molecular Medicine
  • Genetics

Cite this

Utf1 : Goldilocks for ESC bivalency. / Laskowski, Agnieszka I.; Knoepfler, Paul S.

In: Cell Stem Cell, Vol. 11, No. 6, 07.12.2012, p. 732-734.

Research output: Contribution to journalArticle

Laskowski, Agnieszka I. ; Knoepfler, Paul S. / Utf1 : Goldilocks for ESC bivalency. In: Cell Stem Cell. 2012 ; Vol. 11, No. 6. pp. 732-734.
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