The available studies to date provide evidence of a role for NEMG as an in vivo, objective measurement tool to assess neuromuscular function without endangering the patient or requiring sacrifice of the animal model being studied. Our protocol for capturing and quantifying MUAPs in the mdx mouse support the role of EMG as sutiable objective test for therapeutic intervention trials. SEMG still remains somewhat difficult to quantify due to signal interference from skin and subcutaneous tissues, making it a less desirable tool. However, as computer technology evolves, SEMG may have a growing role in quantifying neuromuscular function, having all the advantages of NEMG plus the added benefit of being completely noninvasive. Coupling EMG findings with MR spectroscopy and imaging techniques in muscle allow a clinicician or investigator to get both physiologic and anatomic information of the neuromuscular system.
|Original language||English (US)|
|Number of pages||17|
|Journal||Physical Medicine and Rehabilitation Clinics of North America|
|State||Published - Nov 2005|
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