Use of sonography to evaluate carotid atherosclerosis in the elderly: The cardiovascular health study

Daniel H. O'Leary, Joseph F. Polak, Sidney K. Wolfson, M. Gene Bond, William J Bommer, Sheila Sheth, Bruce M. Psaty, A. Richey Sharrett, Teri A. Manolio

Research output: Contribution to journalArticle

459 Scopus citations

Abstract

Carotid sonography is being performed on more than 5,000 participants in the Cardiovascular Health Study, a prospective, multicenter study of cardiovascular disease in men and women aged 65 years and older. The sonographic methods used to examine and measure the extracranial carotid arteries are described. Initial validation studies were performed on 61 subjects with a mean age of 68.6 years. Analysis of within- and between-sonographer differences and between-reader differences were performed for selected variables. In general, the mean absolute differences for within- and between-sonographer comparisons were small, with even less variability between readers. Variability was less for the common carotid artery than for the internal carotid artery. These data suggest that carotid sonography is a reliable and reproducible method for use in the study of carotid atherosclerosis in population studies.

Original languageEnglish (US)
Pages (from-to)1155-1163
Number of pages9
JournalStroke
Volume22
Issue number9
StatePublished - Sep 1991

Keywords

  • Carotid artery diseases
  • Epidemiology
  • Ultrasonics

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine
  • Neuroscience(all)

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    O'Leary, D. H., Polak, J. F., Wolfson, S. K., Bond, M. G., Bommer, W. J., Sheth, S., Psaty, B. M., Sharrett, A. R., & Manolio, T. A. (1991). Use of sonography to evaluate carotid atherosclerosis in the elderly: The cardiovascular health study. Stroke, 22(9), 1155-1163.