Abstract
Objective - To evaluate sevoflurane as an inhalation anesthetic for thoracotomy in horses. Animals - 18 horses between 2 and 15 years old. Procedure - 4 horses were used to develop surgical techniques and were euthanatized at the end of the procedure. The remaining 14 horses were selected, because they had an episode of bleeding from their lungs during strenuous exercise. General anesthesia was induced with xylazine (1.0 mg/kg of body weight, IV) followed by ketamine (2.0 mg/kg, IV). Anesthesia was maintained with sevoflurane in oxygen delivered via a circle anesthetic breathing circuit. Ventilation was controlled to maintain Paco2 at approximately 45 mm Hg. Neuromuscular blocking drugs (succinylcholine or atracurium) were administered to eliminate spontaneous breathing efforts and to facilitate surgery. Cardiovascular performance was monitored and supported as indicated. Results - 2 of the 14 horses not euthanatized died as a result of ventricular fibrillation. Mean (± SD) duration of anesthesia was 304.9 ± 64.1 minutes for horses that survived and 216.7 ± 85.5 minutes for horses that were euthanatized or died. Our subjective opinion was that sevoflurane afforded good control of anesthetic depth during induction, maintenance, and recovery. Conclusions and Clinical Relevance - Administration of sevoflurane together with neuromuscular blocking drugs provides stable and easily controllable anesthetic management of horses for elective thoracotomy and cardiac manipulation.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 1430-1437 |
| Number of pages | 8 |
| Journal | American Journal of Veterinary Research |
| Volume | 61 |
| Issue number | 11 |
| State | Published - Nov 2000 |
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ASJC Scopus subject areas
- veterinary(all)
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Use of sevoflurane for anesthetic management of horses during thoracotomy. / Aida, Hiroko; Steffey, Eugene; Pascoe, John; Yarbrough, Thomas B.; Takahashi, Toshiyuki; Hiraga, Atsushi; Hobo, Seiji; Smith, Barbara L.; Steffey, Michele A; Jones, James H.
In: American Journal of Veterinary Research, Vol. 61, No. 11, 11.2000, p. 1430-1437.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Use of sevoflurane for anesthetic management of horses during thoracotomy
AU - Aida, Hiroko
AU - Steffey, Eugene
AU - Pascoe, John
AU - Yarbrough, Thomas B.
AU - Takahashi, Toshiyuki
AU - Hiraga, Atsushi
AU - Hobo, Seiji
AU - Smith, Barbara L.
AU - Steffey, Michele A
AU - Jones, James H
PY - 2000/11
Y1 - 2000/11
N2 - Objective - To evaluate sevoflurane as an inhalation anesthetic for thoracotomy in horses. Animals - 18 horses between 2 and 15 years old. Procedure - 4 horses were used to develop surgical techniques and were euthanatized at the end of the procedure. The remaining 14 horses were selected, because they had an episode of bleeding from their lungs during strenuous exercise. General anesthesia was induced with xylazine (1.0 mg/kg of body weight, IV) followed by ketamine (2.0 mg/kg, IV). Anesthesia was maintained with sevoflurane in oxygen delivered via a circle anesthetic breathing circuit. Ventilation was controlled to maintain Paco2 at approximately 45 mm Hg. Neuromuscular blocking drugs (succinylcholine or atracurium) were administered to eliminate spontaneous breathing efforts and to facilitate surgery. Cardiovascular performance was monitored and supported as indicated. Results - 2 of the 14 horses not euthanatized died as a result of ventricular fibrillation. Mean (± SD) duration of anesthesia was 304.9 ± 64.1 minutes for horses that survived and 216.7 ± 85.5 minutes for horses that were euthanatized or died. Our subjective opinion was that sevoflurane afforded good control of anesthetic depth during induction, maintenance, and recovery. Conclusions and Clinical Relevance - Administration of sevoflurane together with neuromuscular blocking drugs provides stable and easily controllable anesthetic management of horses for elective thoracotomy and cardiac manipulation.
AB - Objective - To evaluate sevoflurane as an inhalation anesthetic for thoracotomy in horses. Animals - 18 horses between 2 and 15 years old. Procedure - 4 horses were used to develop surgical techniques and were euthanatized at the end of the procedure. The remaining 14 horses were selected, because they had an episode of bleeding from their lungs during strenuous exercise. General anesthesia was induced with xylazine (1.0 mg/kg of body weight, IV) followed by ketamine (2.0 mg/kg, IV). Anesthesia was maintained with sevoflurane in oxygen delivered via a circle anesthetic breathing circuit. Ventilation was controlled to maintain Paco2 at approximately 45 mm Hg. Neuromuscular blocking drugs (succinylcholine or atracurium) were administered to eliminate spontaneous breathing efforts and to facilitate surgery. Cardiovascular performance was monitored and supported as indicated. Results - 2 of the 14 horses not euthanatized died as a result of ventricular fibrillation. Mean (± SD) duration of anesthesia was 304.9 ± 64.1 minutes for horses that survived and 216.7 ± 85.5 minutes for horses that were euthanatized or died. Our subjective opinion was that sevoflurane afforded good control of anesthetic depth during induction, maintenance, and recovery. Conclusions and Clinical Relevance - Administration of sevoflurane together with neuromuscular blocking drugs provides stable and easily controllable anesthetic management of horses for elective thoracotomy and cardiac manipulation.
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UR - http://www.scopus.com/inward/citedby.url?scp=18844471541&partnerID=8YFLogxK
M3 - Article
C2 - 11108193
AN - SCOPUS:18844471541
VL - 61
SP - 1430
EP - 1437
JO - American Journal of Veterinary Research
JF - American Journal of Veterinary Research
SN - 0002-9645
IS - 11
ER -