Abstract
The diagnostic utility of pentetate indium trisodium in 111 CSF studies, technetium Tc 99m brain scans, and computerized tomographic (CT) scans was evaluated in eight patients in whom coccidioidal meningitis developed following a dust storm in the Central Valley of California. The 111In flow studies and the CT scans demonstrated hydrocephalus in five patients with clinical findings suggesting this complication. Ventriculitis has not previously been diagnosed before death in patients with coccidioidal meningitis; however, it was demonstrated in two patients by the technetium Tc 99m brain scan. Basal meningitis, which is indicative of fungal infection, is also detectable on contrast-enhanced CT scan. The finding that communicating hydrocephalus occurs early in meningitis and interferes with CSF flow into infected basilar regions has important therapeutic implications in that antifungal agents injected into the lumbar subarachnoid space may not reach these regions.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 75-78 |
| Number of pages | 4 |
| Journal | Archives of Internal Medicine |
| Volume | 141 |
| Issue number | 1 |
| DOIs | |
| State | Published - 1981 |
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ASJC Scopus subject areas
- Internal Medicine
Cite this
Use of radiologic modalities in coccidioidal meningitis. / Stadalnik, R. C.; Goldstein, E.; Hoeprich, P. D.; McGahan, John P.
In: Archives of Internal Medicine, Vol. 141, No. 1, 1981, p. 75-78.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Use of radiologic modalities in coccidioidal meningitis
AU - Stadalnik, R. C.
AU - Goldstein, E.
AU - Hoeprich, P. D.
AU - McGahan, John P
PY - 1981
Y1 - 1981
N2 - The diagnostic utility of pentetate indium trisodium in 111 CSF studies, technetium Tc 99m brain scans, and computerized tomographic (CT) scans was evaluated in eight patients in whom coccidioidal meningitis developed following a dust storm in the Central Valley of California. The 111In flow studies and the CT scans demonstrated hydrocephalus in five patients with clinical findings suggesting this complication. Ventriculitis has not previously been diagnosed before death in patients with coccidioidal meningitis; however, it was demonstrated in two patients by the technetium Tc 99m brain scan. Basal meningitis, which is indicative of fungal infection, is also detectable on contrast-enhanced CT scan. The finding that communicating hydrocephalus occurs early in meningitis and interferes with CSF flow into infected basilar regions has important therapeutic implications in that antifungal agents injected into the lumbar subarachnoid space may not reach these regions.
AB - The diagnostic utility of pentetate indium trisodium in 111 CSF studies, technetium Tc 99m brain scans, and computerized tomographic (CT) scans was evaluated in eight patients in whom coccidioidal meningitis developed following a dust storm in the Central Valley of California. The 111In flow studies and the CT scans demonstrated hydrocephalus in five patients with clinical findings suggesting this complication. Ventriculitis has not previously been diagnosed before death in patients with coccidioidal meningitis; however, it was demonstrated in two patients by the technetium Tc 99m brain scan. Basal meningitis, which is indicative of fungal infection, is also detectable on contrast-enhanced CT scan. The finding that communicating hydrocephalus occurs early in meningitis and interferes with CSF flow into infected basilar regions has important therapeutic implications in that antifungal agents injected into the lumbar subarachnoid space may not reach these regions.
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U2 - 10.1001/archinte.141.1.75
DO - 10.1001/archinte.141.1.75
M3 - Article
VL - 141
SP - 75
EP - 78
JO - JAMA Internal Medicine
JF - JAMA Internal Medicine
SN - 2168-6106
IS - 1
ER -