Use of propofol-xylazine and the anderson sling suspension system for recovery of horses from desflurane anesthesia

Eugene Steffey, Robert J Brosnan, Larry D Galuppo, Khursheed R. Mama, Ayako Imai, Lara K. Maxwell, Cynthia A. Cole, Scott D Stanley

Research output: Contribution to journalArticle

10 Citations (Scopus)

Abstract

Objective To characterize the behavior of horses recovering in the Anderson Sling Suspension System after 4 hours of desflurane anesthesia and postdesflurane intravenous (IV) administration of propofol and xylazine. Study Design Experimental study. Animals Healthy horses (n=6), mean±SEM age 12.3±1.8 years; mean weight 556±27 kg. Methods Each horse was anesthetized with xylazine, diazepam, and ketamine IV and anesthesia was maintained with desflurane in O2. At the end of 4 hours of desflurane, each horse was positioned in the sling suspension system and administered propofol-xylazine IV. Recovery events were quantitatively and qualitatively assessed. Venous blood was obtained before and after anesthesia for biochemical and propofol analyses. Results Anesthetic induction and maintenance were without incident. Apnea commonly accompanied propofol administration. All horses had consistent recovery behavior characterized by a smooth, careful, atraumatic return to a standing posture. Conclusions Results of this study support careful, selective clinical use of desflurane, propofol-xylazine, and the Anderson Sling Suspension System to atraumatically transition horses with high anesthetic recovery risk to a wakeful standing posture. Clinical Relevance Technique choices to facilitate individualized, atraumatic recovery of horses from general anesthesia are desirable. Use of IV propofol and xylazine to transition horses from desflurane anesthesia during sling recovery to standing posture may facilitate improved recovery management of high-injury risk equine patients requiring general anesthesia.

Original languageEnglish (US)
Pages (from-to)927-933
Number of pages7
JournalVeterinary Surgery
Volume38
Issue number8
DOIs
StatePublished - Dec 2009

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suspension systems
Xylazine
xylazine
Propofol
Horses
Suspensions
anesthesia
Anesthesia
horses
posture
Posture
anesthetics
General Anesthesia
Anesthetics
desflurane
apnea
Intravenous Anesthesia
diazepam
Ketamine
ketamine

ASJC Scopus subject areas

  • veterinary(all)

Cite this

Use of propofol-xylazine and the anderson sling suspension system for recovery of horses from desflurane anesthesia. / Steffey, Eugene; Brosnan, Robert J; Galuppo, Larry D; Mama, Khursheed R.; Imai, Ayako; Maxwell, Lara K.; Cole, Cynthia A.; Stanley, Scott D.

In: Veterinary Surgery, Vol. 38, No. 8, 12.2009, p. 927-933.

Research output: Contribution to journalArticle

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abstract = "Objective To characterize the behavior of horses recovering in the Anderson Sling Suspension System after 4 hours of desflurane anesthesia and postdesflurane intravenous (IV) administration of propofol and xylazine. Study Design Experimental study. Animals Healthy horses (n=6), mean±SEM age 12.3±1.8 years; mean weight 556±27 kg. Methods Each horse was anesthetized with xylazine, diazepam, and ketamine IV and anesthesia was maintained with desflurane in O2. At the end of 4 hours of desflurane, each horse was positioned in the sling suspension system and administered propofol-xylazine IV. Recovery events were quantitatively and qualitatively assessed. Venous blood was obtained before and after anesthesia for biochemical and propofol analyses. Results Anesthetic induction and maintenance were without incident. Apnea commonly accompanied propofol administration. All horses had consistent recovery behavior characterized by a smooth, careful, atraumatic return to a standing posture. Conclusions Results of this study support careful, selective clinical use of desflurane, propofol-xylazine, and the Anderson Sling Suspension System to atraumatically transition horses with high anesthetic recovery risk to a wakeful standing posture. Clinical Relevance Technique choices to facilitate individualized, atraumatic recovery of horses from general anesthesia are desirable. Use of IV propofol and xylazine to transition horses from desflurane anesthesia during sling recovery to standing posture may facilitate improved recovery management of high-injury risk equine patients requiring general anesthesia.",
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