Use of contrast-enhanced computed tomography to assess angiogenesis in deep digital flexor tendonopathy in a horse

Sarah M. Puchalski, Larry D Galuppo, Clifton P. Drew, Erik R Wisner

Research output: Contribution to journalArticle

33 Citations (Scopus)

Abstract

We compared contrast-enhanced computed tomography (CT) and high field magnetic resonance (MR) imaging in a horse with deep digital flexor tendonopathy. Lesions in the distal extremity were documented grossly and histopathologically. In contrast-enhanced CT, the deep digital flexor tendon lesions were markedly contrast enhancing with evidence of angiogenesis in the core and dorsal border lesions. The lesion morphology was clearly delineated on MR imaging, but without contrast media angiogenesis cannot be identified. Gross examination, histopathologic examination, and CD31 immunohistochemistry confirmed the tendonopathy and an increased presence of small blood vessels. In this horse, deep digital flexor tendon lesions appeared similarly on contrast-enhanced CT and MR imaging. Contrast-enhanced CT may be an alternative to MR imaging for assessing tendon and ligament injury in the digit of the horse.

Original languageEnglish (US)
Pages (from-to)292-297
Number of pages6
JournalVeterinary Radiology and Ultrasound
Volume50
Issue number3
DOIs
StatePublished - May 2009

Fingerprint

Tendinopathy
angiogenesis
computed tomography
lesions (animal)
Horses
magnetic resonance imaging
Tomography
Magnetic Resonance Imaging
horses
tendons
Tendons
Tendon Injuries
Ligaments
Contrast Media
Blood Vessels
ligaments
Extremities
blood vessels
Immunohistochemistry
immunohistochemistry

Keywords

  • Angiogenesis
  • Contrast-enhanced CT
  • Equine deep digital flexor tendon
  • Foot
  • MRI
  • Tendinopathy

ASJC Scopus subject areas

  • veterinary(all)

Cite this

Use of contrast-enhanced computed tomography to assess angiogenesis in deep digital flexor tendonopathy in a horse. / Puchalski, Sarah M.; Galuppo, Larry D; Drew, Clifton P.; Wisner, Erik R.

In: Veterinary Radiology and Ultrasound, Vol. 50, No. 3, 05.2009, p. 292-297.

Research output: Contribution to journalArticle

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