Abstract
The use of botulinum toxin type A to relax the overactive muscles occurring after stroke can improve the quality of life for affected patients. Botulinum toxin is injected locally into tight muscles and allows the patient improved function, such as cleaning the hand or assisting with dressing. A large multicenter, double-blind, placebo-controlled trial demonstrated improvement in tone and functional disability in those patients with poststroke spasticity of the hand and wrist treated with botulinum toxin. Benefits were maintained throughout the 12-week study. Side effects of the injections were mild and self-limited. Botulinum toxin type A injections for upper extremity spasticity are safe and efficacious, and should be considered as first choice in the treatment of this disorder.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 271-277 |
| Number of pages | 7 |
| Journal | Expert Review of Neurotherapeutics |
| Volume | 3 |
| Issue number | 3 |
| DOIs | |
| State | Published - May 1 2003 |
| Externally published | Yes |
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Keywords
- BOTOX
- Botulinum toxin
- Spasticity
- Stroke
ASJC Scopus subject areas
- Neuroscience(all)
- Clinical Neurology
- Pharmacology (medical)
Cite this
Use of botulinum toxin type A in poststroke spasticity. / Brashear, Allison.
In: Expert Review of Neurotherapeutics, Vol. 3, No. 3, 01.05.2003, p. 271-277.Research output: Contribution to journal › Review article
}
TY - JOUR
T1 - Use of botulinum toxin type A in poststroke spasticity
AU - Brashear, Allison
PY - 2003/5/1
Y1 - 2003/5/1
N2 - The use of botulinum toxin type A to relax the overactive muscles occurring after stroke can improve the quality of life for affected patients. Botulinum toxin is injected locally into tight muscles and allows the patient improved function, such as cleaning the hand or assisting with dressing. A large multicenter, double-blind, placebo-controlled trial demonstrated improvement in tone and functional disability in those patients with poststroke spasticity of the hand and wrist treated with botulinum toxin. Benefits were maintained throughout the 12-week study. Side effects of the injections were mild and self-limited. Botulinum toxin type A injections for upper extremity spasticity are safe and efficacious, and should be considered as first choice in the treatment of this disorder.
AB - The use of botulinum toxin type A to relax the overactive muscles occurring after stroke can improve the quality of life for affected patients. Botulinum toxin is injected locally into tight muscles and allows the patient improved function, such as cleaning the hand or assisting with dressing. A large multicenter, double-blind, placebo-controlled trial demonstrated improvement in tone and functional disability in those patients with poststroke spasticity of the hand and wrist treated with botulinum toxin. Benefits were maintained throughout the 12-week study. Side effects of the injections were mild and self-limited. Botulinum toxin type A injections for upper extremity spasticity are safe and efficacious, and should be considered as first choice in the treatment of this disorder.
KW - BOTOX
KW - Botulinum toxin
KW - Spasticity
KW - Stroke
UR - http://www.scopus.com/inward/record.url?scp=0037799871&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0037799871&partnerID=8YFLogxK
U2 - 10.1586/14737175.3.3.271
DO - 10.1586/14737175.3.3.271
M3 - Review article
C2 - 19810893
AN - SCOPUS:0037799871
VL - 3
SP - 271
EP - 277
JO - Expert Review of Neurotherapeutics
JF - Expert Review of Neurotherapeutics
SN - 1473-7175
IS - 3
ER -