Ursodeoxycholic acid treatment in primary sclerosing cholangitis

James H. Tabibian, Keith D. Lindor

Research output: Chapter in Book/Report/Conference proceedingChapter


Primary sclerosing cholangitis (PSC) is a chronic, idiopathic liver disease which, despite extensive laboratory-based investigation, translational studies, and clinical trials, lacks established medical treatment. In this chapter, we provide a succinct, comprehensive review of research regarding the potential role for ursodeoxycholic acid as a pharmacotherapy for PSC.

Original languageEnglish (US)
Title of host publicationPrimary Sclerosing Cholangitis: Current Understanding, Management, and Future Developments
PublisherSpringer International Publishing
Number of pages8
ISBN (Electronic)9783319409085
ISBN (Print)9783319409061
StatePublished - Jan 1 2016


  • Algorithm
  • Bile acids
  • Biliary tract diseases
  • Cholestasis
  • Cholestatic liver disease
  • Medical management
  • Outcomes
  • Pharmacotherapy
  • Pruritus
  • Quality of life

ASJC Scopus subject areas

  • Medicine(all)


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