Urogenital symptoms in women with Tarlov cysts

Molly Baker, Machelle Wilson, Stacey J Wallach

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

Aim: To describe the clinical findings and urogenital symptoms associated with sacral perineural cysts (Tarlov cysts). Methods: A retrospective chart review including 65 female patients with Tarlov cysts was completed. Clinical findings were collected from a database of subjects seen in our institution's urogynecology and neurosurgery clinics between 2004 and 2015. A statistical analysis was performed to test for any correlation between cyst size or location, and patient symptoms or examination findings. Results: Tarlov cysts were most commonly located from S2 to S3 (73%), and ranged in size from 1 to 2cm (55%). Frequently reported symptoms included lower back pain (83%, 95% confidence interval [CI] 0.71-0.91), lower extremity radiculopathy (75%, CI 0.63-0.85), positional pain (62%, CI 0.50-0.73), urinary urgency (54%, CI 0.41-0.66) and urinary frequency (48%, CI 0.35-0.61). Common urodynamic findings included an early sensation of filling (70%), involuntary detrusor contractions (33%), urethral instability (33%) and stress urinary incontinence (33%). A statistical analysis comparing cyst size and location to clinical findings was significant for a correlation between an S2 location and central nervous system symptoms (P=0.02), larger cyst size and urinary dysfunction (P=0.05) and smaller cyst size and an early sensation of filling (P=0.05). Conclusion: Patients with symptomatic sacral Tarlov cysts frequently report pain and neuropathy related to the lower back, pelvis and urogenital system. As compared to the general population, urinary urgency and urodynamic findings associated with urgency were more frequent in our patient sample. These findings suggest that Tarlov cysts may have a clinically significant impact on urogenital function.

Original languageEnglish (US)
JournalJournal of Obstetrics and Gynaecology Research
DOIs
StateAccepted/In press - Jan 1 2018

Fingerprint

Tarlov Cysts
Confidence Intervals
Cysts
Urodynamics
Urogenital System
Pain
Radiculopathy
Stress Urinary Incontinence
Neurosurgery
Low Back Pain
Pelvis
Lower Extremity
Central Nervous System
Databases

Keywords

  • Neurology
  • Pelvic pain
  • Sexual dysfunction
  • Urinary incontinence
  • Urodynamics

ASJC Scopus subject areas

  • Obstetrics and Gynecology

Cite this

Urogenital symptoms in women with Tarlov cysts. / Baker, Molly; Wilson, Machelle; Wallach, Stacey J.

In: Journal of Obstetrics and Gynaecology Research, 01.01.2018.

Research output: Contribution to journalArticle

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abstract = "Aim: To describe the clinical findings and urogenital symptoms associated with sacral perineural cysts (Tarlov cysts). Methods: A retrospective chart review including 65 female patients with Tarlov cysts was completed. Clinical findings were collected from a database of subjects seen in our institution's urogynecology and neurosurgery clinics between 2004 and 2015. A statistical analysis was performed to test for any correlation between cyst size or location, and patient symptoms or examination findings. Results: Tarlov cysts were most commonly located from S2 to S3 (73{\%}), and ranged in size from 1 to 2cm (55{\%}). Frequently reported symptoms included lower back pain (83{\%}, 95{\%} confidence interval [CI] 0.71-0.91), lower extremity radiculopathy (75{\%}, CI 0.63-0.85), positional pain (62{\%}, CI 0.50-0.73), urinary urgency (54{\%}, CI 0.41-0.66) and urinary frequency (48{\%}, CI 0.35-0.61). Common urodynamic findings included an early sensation of filling (70{\%}), involuntary detrusor contractions (33{\%}), urethral instability (33{\%}) and stress urinary incontinence (33{\%}). A statistical analysis comparing cyst size and location to clinical findings was significant for a correlation between an S2 location and central nervous system symptoms (P=0.02), larger cyst size and urinary dysfunction (P=0.05) and smaller cyst size and an early sensation of filling (P=0.05). Conclusion: Patients with symptomatic sacral Tarlov cysts frequently report pain and neuropathy related to the lower back, pelvis and urogenital system. As compared to the general population, urinary urgency and urodynamic findings associated with urgency were more frequent in our patient sample. These findings suggest that Tarlov cysts may have a clinically significant impact on urogenital function.",
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N2 - Aim: To describe the clinical findings and urogenital symptoms associated with sacral perineural cysts (Tarlov cysts). Methods: A retrospective chart review including 65 female patients with Tarlov cysts was completed. Clinical findings were collected from a database of subjects seen in our institution's urogynecology and neurosurgery clinics between 2004 and 2015. A statistical analysis was performed to test for any correlation between cyst size or location, and patient symptoms or examination findings. Results: Tarlov cysts were most commonly located from S2 to S3 (73%), and ranged in size from 1 to 2cm (55%). Frequently reported symptoms included lower back pain (83%, 95% confidence interval [CI] 0.71-0.91), lower extremity radiculopathy (75%, CI 0.63-0.85), positional pain (62%, CI 0.50-0.73), urinary urgency (54%, CI 0.41-0.66) and urinary frequency (48%, CI 0.35-0.61). Common urodynamic findings included an early sensation of filling (70%), involuntary detrusor contractions (33%), urethral instability (33%) and stress urinary incontinence (33%). A statistical analysis comparing cyst size and location to clinical findings was significant for a correlation between an S2 location and central nervous system symptoms (P=0.02), larger cyst size and urinary dysfunction (P=0.05) and smaller cyst size and an early sensation of filling (P=0.05). Conclusion: Patients with symptomatic sacral Tarlov cysts frequently report pain and neuropathy related to the lower back, pelvis and urogenital system. As compared to the general population, urinary urgency and urodynamic findings associated with urgency were more frequent in our patient sample. These findings suggest that Tarlov cysts may have a clinically significant impact on urogenital function.

AB - Aim: To describe the clinical findings and urogenital symptoms associated with sacral perineural cysts (Tarlov cysts). Methods: A retrospective chart review including 65 female patients with Tarlov cysts was completed. Clinical findings were collected from a database of subjects seen in our institution's urogynecology and neurosurgery clinics between 2004 and 2015. A statistical analysis was performed to test for any correlation between cyst size or location, and patient symptoms or examination findings. Results: Tarlov cysts were most commonly located from S2 to S3 (73%), and ranged in size from 1 to 2cm (55%). Frequently reported symptoms included lower back pain (83%, 95% confidence interval [CI] 0.71-0.91), lower extremity radiculopathy (75%, CI 0.63-0.85), positional pain (62%, CI 0.50-0.73), urinary urgency (54%, CI 0.41-0.66) and urinary frequency (48%, CI 0.35-0.61). Common urodynamic findings included an early sensation of filling (70%), involuntary detrusor contractions (33%), urethral instability (33%) and stress urinary incontinence (33%). A statistical analysis comparing cyst size and location to clinical findings was significant for a correlation between an S2 location and central nervous system symptoms (P=0.02), larger cyst size and urinary dysfunction (P=0.05) and smaller cyst size and an early sensation of filling (P=0.05). Conclusion: Patients with symptomatic sacral Tarlov cysts frequently report pain and neuropathy related to the lower back, pelvis and urogenital system. As compared to the general population, urinary urgency and urodynamic findings associated with urgency were more frequent in our patient sample. These findings suggest that Tarlov cysts may have a clinically significant impact on urogenital function.

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KW - Pelvic pain

KW - Sexual dysfunction

KW - Urinary incontinence

KW - Urodynamics

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