Urinary tract manifestations of protothecosis in dogs

Barrak M. Pressler, Jody L. Gookin, Jane E Sykes, Alice M. Wolf, Shelly L. Vaden

Research output: Contribution to journalArticle

22 Citations (Scopus)

Abstract

Records of 13 dogs with systemic infection with Prototheca sp. from 3 veterinary teaching hospitals were reviewed. Acute renal failure secondary to disseminated infection with Prototheca zopfii was diagnosed in 2 dogs. In 1 dog, acute renal failure developed during administration of immunosuppressive drugs for treatment of anterior uveitis. During diagnostic evaluation of this dog, Prototheca sp. organisms were noted in urine sediment and renal biopsy specimens. In the 2nd dog, acute renal failure was diagnosed after treatment for bacterial cystitis. After diagnosis of protothecosis, organisms were successfully isolated by aerobic urine culture. Both dogs with acute renal failure did not respond to conventional medical therapy. In total, Prototheca sp. was noted in urine sediment in 4 of 8 dogs and successfully cultured from urine in 5 of 7 dogs. Four of 5 dogs had organisms noted in the kidneys on histopathologic examination. In all dogs, the species identified was P zopfii. Sensitivity testing of 3 isolates revealed wide differences in in vitro drug resistance. Examination and culture of urine is recommended as a practical method for diagnosis of systemic infection with Prototheca sp.

Original languageEnglish (US)
Pages (from-to)115-119
Number of pages5
JournalJournal of Veterinary Internal Medicine
Volume19
Issue number1
DOIs
StatePublished - Jan 2005

Fingerprint

urinary tract
Urinary Tract
Prototheca
Dogs
dogs
renal failure
urine
Acute Kidney Injury
Urine
organisms
Infection
kidneys
infection
Anterior Uveitis
Animal Hospitals
Kidney
cystitis
immunosuppressive agents
sediments
Cystitis

Keywords

  • Acute renal failure
  • Algae
  • Prototheca wickerhamii
  • Prototheca zopfii
  • Urinary tract infection
  • Urine culture

ASJC Scopus subject areas

  • veterinary(all)

Cite this

Urinary tract manifestations of protothecosis in dogs. / Pressler, Barrak M.; Gookin, Jody L.; Sykes, Jane E; Wolf, Alice M.; Vaden, Shelly L.

In: Journal of Veterinary Internal Medicine, Vol. 19, No. 1, 01.2005, p. 115-119.

Research output: Contribution to journalArticle

Pressler, Barrak M. ; Gookin, Jody L. ; Sykes, Jane E ; Wolf, Alice M. ; Vaden, Shelly L. / Urinary tract manifestations of protothecosis in dogs. In: Journal of Veterinary Internal Medicine. 2005 ; Vol. 19, No. 1. pp. 115-119.
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