Urinary effects of morphine in preterm infants

B. O S Bengtsson, S. L. Wootton-Gorges, Francis R Poulain, Michael P. Sherman

Research output: Contribution to journalArticle

11 Citations (Scopus)

Abstract

Aim: To describe the association between morphine administration in preterm infants, hydronephrosis, and renal dysfunction. Methods: The findings were based on serial ultrasound examinations and blood studies. Results: Two preterm infants had bladder distension and hydronephrosis after they received intravenous morphine for analgesia. Morphine was used at a low dose. Each patient had a normal urine output and normal serum creatinine before the signs and symptoms of urinary retention were observed. Within 24 h of morphine administration, each infant concurrently developed oliguria and elevation of the serum creatinine. Cessation of morphine and urinary drainage resulted in rapid and complete resolution of the hydronephrosis and the elevated creatinine. Conclusion: Morphine, even at low dosages, can be associated with hydronephrosis in hospitalized preterm infants.

Original languageEnglish (US)
Pages (from-to)251-253
Number of pages3
JournalActa Paediatrica, International Journal of Paediatrics
Volume92
Issue number2
StatePublished - 2003

Fingerprint

Premature Infants
Morphine
Hydronephrosis
Creatinine
Oliguria
Urinary Retention
Serum
Analgesia
Signs and Symptoms
Drainage
Urinary Bladder
Urine
Kidney

Keywords

  • Bladder distension
  • Creatinine
  • Hydronephrosis
  • Oliguria
  • Ultrasound

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health

Cite this

Bengtsson, B. O. S., Wootton-Gorges, S. L., Poulain, F. R., & Sherman, M. P. (2003). Urinary effects of morphine in preterm infants. Acta Paediatrica, International Journal of Paediatrics, 92(2), 251-253.

Urinary effects of morphine in preterm infants. / Bengtsson, B. O S; Wootton-Gorges, S. L.; Poulain, Francis R; Sherman, Michael P.

In: Acta Paediatrica, International Journal of Paediatrics, Vol. 92, No. 2, 2003, p. 251-253.

Research output: Contribution to journalArticle

Bengtsson, BOS, Wootton-Gorges, SL, Poulain, FR & Sherman, MP 2003, 'Urinary effects of morphine in preterm infants', Acta Paediatrica, International Journal of Paediatrics, vol. 92, no. 2, pp. 251-253.
Bengtsson, B. O S ; Wootton-Gorges, S. L. ; Poulain, Francis R ; Sherman, Michael P. / Urinary effects of morphine in preterm infants. In: Acta Paediatrica, International Journal of Paediatrics. 2003 ; Vol. 92, No. 2. pp. 251-253.
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