Abstract
Objective: To establish test-retest reliability of flexor carpi radialis (FCR) H-reflexes in non-disabled and stroke participants. We also investigated inter-limb differences and effects of chronicity post-stroke compared to non-disabled group and age-related effects in the non-disabled group. Methods: Sixteen chronic stroke and twenty-two non-disabled participants were recruited. Bilateral FCR H-reflexes were tested on two separate days by stimulating the median nerve and recording surface electromyography responses. FCR recruitment curves were plotted for H-reflex (H) and motor (M) waves and normalized as a percentage of maximal M-wave (ordinate) and motor threshold (abscissa). Statistics: Intraclass correlation coefficients [two-way mixed model-ICC (1, 2)], one-way ANOVA, Bland-Altman plots, standard error of measurement (SEM), and smallest real difference (SRD). Results: ICCs ranged from 0.55 to 0.95 (stroke) and 0.69-0.88 (non-disabled). SEM% (% of the mean) ranged from 9% to 24% (stroke) and 18-38% (non-disabled); SRD% ranged from 18% to 66% (stroke) and 6% to 50% (non-disabled). H-reflex amplitude and slope were greater in the paretic vs. non-paretic arm post-stroke (p= 0.07 and 0.01, respectively) and the paretic arm vs. non-disabled participants (p= 0.007 and 0.002, respectively). Stroke participants with longer chronicity (mean 9.4. years) revealed a significantly greater Hslp/Mslp on the paretic side compared to shorter chronicity (2.5. years; p= 0.05). Mean Hslp/Mslp was significantly greater in the young (mean 29. years) compared to the older group (62. years; p= 0.045). Conclusions: These results establish reliability of FCR H-reflexes in stroke and non-disabled participants. SEM and SRD measurements can be used to interpret recovery patterns and longitudinal effects of therapeutic interventions. Significance: FCR H-reflex amplitude and slope can be reliably measured and used to investigate neurophysiological mechanisms of motor recovery post-stroke.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 1606-1615 |
| Number of pages | 10 |
| Journal | Clinical Neurophysiology |
| Volume | 123 |
| Issue number | 8 |
| DOIs | |
| State | Published - Aug 1 2012 |
| Externally published | Yes |
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Keywords
- Recovery
- Reflex
- Reliability
- Stroke
- Upper-extremity
ASJC Scopus subject areas
- Clinical Neurology
- Neurology
- Physiology (medical)
- Sensory Systems
Cite this
Upper-extremity H-reflex measurement post-stroke : Reliability and inter-limb differences. / Phadke, Chetan P.; Robertson, Christopher T.; Condliffe, Elizabeth G.; Patten, Carolynn.
In: Clinical Neurophysiology, Vol. 123, No. 8, 01.08.2012, p. 1606-1615.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Upper-extremity H-reflex measurement post-stroke
T2 - Reliability and inter-limb differences
AU - Phadke, Chetan P.
AU - Robertson, Christopher T.
AU - Condliffe, Elizabeth G.
AU - Patten, Carolynn
PY - 2012/8/1
Y1 - 2012/8/1
N2 - Objective: To establish test-retest reliability of flexor carpi radialis (FCR) H-reflexes in non-disabled and stroke participants. We also investigated inter-limb differences and effects of chronicity post-stroke compared to non-disabled group and age-related effects in the non-disabled group. Methods: Sixteen chronic stroke and twenty-two non-disabled participants were recruited. Bilateral FCR H-reflexes were tested on two separate days by stimulating the median nerve and recording surface electromyography responses. FCR recruitment curves were plotted for H-reflex (H) and motor (M) waves and normalized as a percentage of maximal M-wave (ordinate) and motor threshold (abscissa). Statistics: Intraclass correlation coefficients [two-way mixed model-ICC (1, 2)], one-way ANOVA, Bland-Altman plots, standard error of measurement (SEM), and smallest real difference (SRD). Results: ICCs ranged from 0.55 to 0.95 (stroke) and 0.69-0.88 (non-disabled). SEM% (% of the mean) ranged from 9% to 24% (stroke) and 18-38% (non-disabled); SRD% ranged from 18% to 66% (stroke) and 6% to 50% (non-disabled). H-reflex amplitude and slope were greater in the paretic vs. non-paretic arm post-stroke (p= 0.07 and 0.01, respectively) and the paretic arm vs. non-disabled participants (p= 0.007 and 0.002, respectively). Stroke participants with longer chronicity (mean 9.4. years) revealed a significantly greater Hslp/Mslp on the paretic side compared to shorter chronicity (2.5. years; p= 0.05). Mean Hslp/Mslp was significantly greater in the young (mean 29. years) compared to the older group (62. years; p= 0.045). Conclusions: These results establish reliability of FCR H-reflexes in stroke and non-disabled participants. SEM and SRD measurements can be used to interpret recovery patterns and longitudinal effects of therapeutic interventions. Significance: FCR H-reflex amplitude and slope can be reliably measured and used to investigate neurophysiological mechanisms of motor recovery post-stroke.
AB - Objective: To establish test-retest reliability of flexor carpi radialis (FCR) H-reflexes in non-disabled and stroke participants. We also investigated inter-limb differences and effects of chronicity post-stroke compared to non-disabled group and age-related effects in the non-disabled group. Methods: Sixteen chronic stroke and twenty-two non-disabled participants were recruited. Bilateral FCR H-reflexes were tested on two separate days by stimulating the median nerve and recording surface electromyography responses. FCR recruitment curves were plotted for H-reflex (H) and motor (M) waves and normalized as a percentage of maximal M-wave (ordinate) and motor threshold (abscissa). Statistics: Intraclass correlation coefficients [two-way mixed model-ICC (1, 2)], one-way ANOVA, Bland-Altman plots, standard error of measurement (SEM), and smallest real difference (SRD). Results: ICCs ranged from 0.55 to 0.95 (stroke) and 0.69-0.88 (non-disabled). SEM% (% of the mean) ranged from 9% to 24% (stroke) and 18-38% (non-disabled); SRD% ranged from 18% to 66% (stroke) and 6% to 50% (non-disabled). H-reflex amplitude and slope were greater in the paretic vs. non-paretic arm post-stroke (p= 0.07 and 0.01, respectively) and the paretic arm vs. non-disabled participants (p= 0.007 and 0.002, respectively). Stroke participants with longer chronicity (mean 9.4. years) revealed a significantly greater Hslp/Mslp on the paretic side compared to shorter chronicity (2.5. years; p= 0.05). Mean Hslp/Mslp was significantly greater in the young (mean 29. years) compared to the older group (62. years; p= 0.045). Conclusions: These results establish reliability of FCR H-reflexes in stroke and non-disabled participants. SEM and SRD measurements can be used to interpret recovery patterns and longitudinal effects of therapeutic interventions. Significance: FCR H-reflex amplitude and slope can be reliably measured and used to investigate neurophysiological mechanisms of motor recovery post-stroke.
KW - Recovery
KW - Reflex
KW - Reliability
KW - Stroke
KW - Upper-extremity
UR - http://www.scopus.com/inward/record.url?scp=84863196732&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84863196732&partnerID=8YFLogxK
U2 - 10.1016/j.clinph.2011.12.012
DO - 10.1016/j.clinph.2011.12.012
M3 - Article
C2 - 22277759
AN - SCOPUS:84863196732
VL - 123
SP - 1606
EP - 1615
JO - Clinical Neurophysiology
JF - Clinical Neurophysiology
SN - 1388-2457
IS - 8
ER -