Update on the optimal use of voriconazole for invasive fungal infections

Research output: Contribution to journalArticle

53 Scopus citations

Abstract

Voriconazole is an extended-spectrum triazole with excellent bioavailability that has now become the treatment of choice for aspergillosis. It has a unique side effect profile compared with other azoles, as well as a number of clinically important drug-drug interactions. These factors, along with a correlation between increased serum levels and improved outcomes, have prompted an interest in therapeutic drug monitoring of this agent. The pharmacology and clinical outcomes data of voriconazole are presented in this review.

Original languageEnglish (US)
Pages (from-to)43-53
Number of pages11
JournalInfection and Drug Resistance
Volume4
Issue number1
DOIs
StatePublished - 2011

Keywords

  • Aspergillosis
  • Candidiasis
  • Therapeutic drug monitoring
  • Voriconazole

ASJC Scopus subject areas

  • Infectious Diseases
  • Pharmacology (medical)
  • Pharmacology

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