Abstract
Purpose: To describe a case of iris melanoma for which a patient refused treatment for 15 years, and the complications that resulted. Methods: Single case report. Results: A 52-year-old white man was evaluated for a suspicious pigmented lesion of the left iris. He was followed closely with serial examinations and ultrasound biomicroscopy, and he refused therapy when the lesion showed growth 15 years after presentation. The patient subsequently developed recurrent hyphema, intraocular pressure up to 55 mmHg, and glaucomatous optic neuropathy. He eventually underwent iodine-125 brachytherapy resulting in tumor regression and improvement of intraocular pressure. Conclusion: Untreated iris melanoma can develop complications such as recurrent hyphema and glaucoma with irreversible optic nerve damage. Treatment of slow-growing iris melanoma must be considered to prevent complications.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 44-47 |
| Number of pages | 4 |
| Journal | Retinal Cases and Brief Reports |
| Volume | 10 |
| Issue number | 1 |
| DOIs | |
| State | Published - Jan 1 2016 |
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Keywords
- Glaucoma
- Iodine-125 brachytherapy
- Iris melanoma
- Uveal melanoma
ASJC Scopus subject areas
- Ophthalmology
Cite this
Untreated IRIS melanoma complicated by hyphema and uncontrolled glaucoma responsive to IODINE-125 brachytherapy. / Chang, Melinda Y; McCannel, Colin A.; McCannel, Tara A.
In: Retinal Cases and Brief Reports, Vol. 10, No. 1, 01.01.2016, p. 44-47.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Untreated IRIS melanoma complicated by hyphema and uncontrolled glaucoma responsive to IODINE-125 brachytherapy
AU - Chang, Melinda Y
AU - McCannel, Colin A.
AU - McCannel, Tara A.
PY - 2016/1/1
Y1 - 2016/1/1
N2 - Purpose: To describe a case of iris melanoma for which a patient refused treatment for 15 years, and the complications that resulted. Methods: Single case report. Results: A 52-year-old white man was evaluated for a suspicious pigmented lesion of the left iris. He was followed closely with serial examinations and ultrasound biomicroscopy, and he refused therapy when the lesion showed growth 15 years after presentation. The patient subsequently developed recurrent hyphema, intraocular pressure up to 55 mmHg, and glaucomatous optic neuropathy. He eventually underwent iodine-125 brachytherapy resulting in tumor regression and improvement of intraocular pressure. Conclusion: Untreated iris melanoma can develop complications such as recurrent hyphema and glaucoma with irreversible optic nerve damage. Treatment of slow-growing iris melanoma must be considered to prevent complications.
AB - Purpose: To describe a case of iris melanoma for which a patient refused treatment for 15 years, and the complications that resulted. Methods: Single case report. Results: A 52-year-old white man was evaluated for a suspicious pigmented lesion of the left iris. He was followed closely with serial examinations and ultrasound biomicroscopy, and he refused therapy when the lesion showed growth 15 years after presentation. The patient subsequently developed recurrent hyphema, intraocular pressure up to 55 mmHg, and glaucomatous optic neuropathy. He eventually underwent iodine-125 brachytherapy resulting in tumor regression and improvement of intraocular pressure. Conclusion: Untreated iris melanoma can develop complications such as recurrent hyphema and glaucoma with irreversible optic nerve damage. Treatment of slow-growing iris melanoma must be considered to prevent complications.
KW - Glaucoma
KW - Iodine-125 brachytherapy
KW - Iris melanoma
KW - Uveal melanoma
UR - http://www.scopus.com/inward/record.url?scp=84954159411&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84954159411&partnerID=8YFLogxK
U2 - 10.1097/ICB.0000000000000171
DO - 10.1097/ICB.0000000000000171
M3 - Article
C2 - 26383516
AN - SCOPUS:84954159411
VL - 10
SP - 44
EP - 47
JO - Retinal Cases and Brief Reports
JF - Retinal Cases and Brief Reports
SN - 1935-1089
IS - 1
ER -